Dose | Initial Infusion Rate | Maintenance Infusion Rate |
Intravenous Administration | ||
PI | ||
300 to 600 mg/kg every 3 to 4 weeks based on clinical response | 0.5 mL/kg/hr (0.8 mg/kg/min) | Increase every 30 minutes |
MMN | ||
Dose range 0.5 to | 0.5mL/kg/hr (0.8 mg/kg/min) | Infusion rate may be advanced if tolerated to 5.4 mL/kg/hr (9 mg/kg/min) |
Subcutaneous Administration: | ||
PI | ||
Initial Dose is 1.37 × previous intravenous dose divided by # of weeks between intravenous doses. Maintenance dose is based on clinical response and target IgG trough level . | 40 kg BW and greater: 30 mL/site at 20 mL/hr/site. Under 40 kg BW: | 40 kg BW and greater: Under 40 kg BW: 20 mL/site at 15 to 20 mL/hr/site |