Invokamet Prescribing & Dosing Schedule

Dosage & Administration Drug label People also ask

Invokamet (canagliflozin / metformin)

canagliflozin 150 MG / metformin hydrochloride 1000 MG Oral Tablet [Invokamet]

Dosage & Administration

* Individualize starting dose based on the patient's current regimen and renal function ( 2.2, 2.3, 2.4)
* Initiation of INVOKAMET or INVOKAMET XR is not recommended in patients with an eGFR less than 45 mL/min/1.73 m 2, due to the metformin component ( 2.4)
* INVOKAMET: one tablet, twice daily with meals, recommended starting dose of canagliflozin is 50 mg twice daily and metformin HCl 500 mg twice daily ( 2.2)
* INVOKAMET XR: two tablets, once daily with the morning meal. Swallow whole. Never crush, cut, or chew ( 2.2)
* Canagliflozin dose can be increased to a total daily dose of 300 mg in patients tolerating 100 mg who have an eGFR of 60 mL/min/1.73 m 2 or greater and require additional glycemic control. Do not exceed a total daily canagliflozin dose of 300 mg ( 2.2)
* Gradually escalate metformin HCl dose to reduce the gastrointestinal side effects while not exceeding a total daily dose of 2,000 mg ( 2.3)
* Assess renal function before initiating and as clinically indicated ( 2.1, 2.3)
* Dose adjustment for patients with renal impairment may be required ( 2.4)
* Adjust canagliflozin dose when taken with an UDP-Glucuronosyltransferase (UGT) inducer ( 2.5, 7.2)
* May need to be discontinued at time of, or prior to, iodinated contrast imaging procedures ( 2.6)

drug label

Invokamet Prescribing Information

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financial assistance

Invokamet Financial Assistance Options

Copay savings program

Enroll in Patient Savings Program

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Foundation programs

J & J Patient Assistance Foundation Eligibility Check

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and copays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.

How to sign up

Patients submit proof of out-of-pocket drug costs to charities for reimbursement

Invokamet FAQs

How is the dosage of Invokamet ?Invokamet is available in 1 dosages, including 150-1,000 mg Tab

What does Invokamet treat?Invokamet treats Type 2 Diabetes Mellitus

What is Invokamet made of?Invokamet contains canagliflozin / metformin which is a Biguanide

How Is Invokamet Administered?Invokamet is administered as a Oral Pill

FAQ Data Source

Dosage & Administration

Dosage & Administration

drug label

Invokamet Prescribing Information

financial assistance

Invokamet Financial Assistance Options

Copay savings program

Foundation programs

people also ask

Invokamet FAQs