Otezla

(apremilast)
apremilast 10 MG Oral Tablet [Otezla]apremilast 20 MG Oral Tablet [Otezla]
View 1 more
NO BLACK BOX WARNING

Dosage & administration


drug label

Otezla prescribing information

samples

Request Otezla samples

Online Sample Form
Learn More

prior authorization

Otezla prior authorization resources

Most recent Otezla prior authorization forms

View By Payer
Updated: May 25, 2023Independence Health - Value Formulary Immune Modulating Therapy Prior Authorization Form
Updated: May 25, 2023Independence Health - Select Formulary Immune Modulating Therapy Prior Authorization Form

PDF
Letter of Medical Necessity: English

PDF
Letter of Medical Necessity: Spanish

PDF
Prior Authorization Checklist

PDF
Otezla HCP Request Form

PDF
Otezla Specialty Pharmacy Start form (if HCP office wants SP to co-ordinate PA)
Learn More

Benefits investigation

PDF
Otezla HCP Request Form

PDF
Otezla Specialty Pharmacy Start form (if HCP office wants SP to co-ordinate PA)
Learn More

pharmacy

Otezla preferred pharmacy

PDF
Pharmacy List

financial assistance

Otezla financial assistance options

Co-pay savings program

commercial only
Enroll in Patient Savings Program
Learn More

Bridge program

commercial only

OTHER
Bridge Program
Learn More

Foundation programs

under insured
no insurance
goverment insurance
65+

OTHER
Amgen Safety Net Foundation Eligibility Check
Learn More

patient education

Otezla patient education

Getting started on Otezla

To share resource; ask patient to:
1.Pull out phone
2.Open camera
3.Scan QR code with camera
4.Tap link

Patient toolkit

PDF
Patient Starter Kit/Brochure
ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

PDF
Plaque Psoriasis Symptom Tracker
ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

PDF
PsA Symptom Tracker
ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

BRAND PAGE
About Otezla: PsO
ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

BRAND PAGE
Side Effects: PsO
ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

OTHER
Patient Stories: PsO
ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

IMAGE
Before & After: PsO
ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

OTHER
Doctor Discussion Guide: PsO
ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

OTHER
View How to Take Otezla: PsO
ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

PDF
Otezla Patient Roadmap (Getting Your Otezla Prescription)
ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

BRAND PAGE
About Otezla: Oral Ulcers in Bechet's Disease
ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

BRAND PAGE
About Otezla: PsA
ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

OTHER
Patient Stories: PsA
ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

OTHER
Doctor Discussion Guide: PsA
ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

OTHER
View How to Take Otezla: PsA
ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

BRAND PAGE
Side Effects: PsA
ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link
Learn More

Other resources

Learn More

people also ask

Otezla FAQs

Is there a pregnancy exposure registry for OTEZLA?Yes, there is a pregnancy exposure registry for OTEZLA that monitors pregnancy outcomes in women exposed to OTEZLA during pregnancy. For more information about the registry or to report a pregnancy while on OTEZLA, contact 1-877-311-8972 or visit https://mothertobaby.org/ongoing-study/otezla/.
What is the risk of major birth defects or adverse outcomes with OTEZLA use in pregnant women?Available pharmacovigilance data with OTEZLA use in pregnant women have not established a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes, but these data are extremely limited. Based on findings from animal reproduction studies, OTEZLA may increase the risk for fetal loss. The background risk of major birth defects and miscarriage for the indicated populations is unknown. All pregnancies have a background risk of birth defect, loss, or other adverse outcomes. In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2-4% and 15-20%, respectively. Pregnant women should consult with their healthcare provider and consider pregnancy planning and prevention.
What are the animal data on OTEZLA use in pregnancy?In embryo-fetal development studies, pregnant cynomolgus monkeys administered apremilast (OTEZLA) during organogenesis resulted in dose-related increases in abortion/embryo-fetal death at doses approximately 2.1-times the maximum recommended human therapeutic dose (MRHD) and greater. No abortifacient effects were observed at a dose approximately 1.4-times the MRHD. No teratogenic effects were observed in mice administered apremilast during organogenesis up to exposures 4.0-times the MRHD. Apremilast distributed across the placenta into the fetal compartment in mice and monkeys. Pregnant women should consult with their healthcare provider and consider pregnancy planning and prevention.
Is apremilast (OTEZLA) present in human milk?There are no data on the presence of apremilast in human milk. However, apremilast was detected in the milk of lactating mice. When a drug is present in animal milk, it is likely that the drug will be present in human milk. The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for OTEZLA and any potential adverse effects on the breastfed infant from OTEZLA or from the underlying maternal condition. Women should consult with their healthcare provider.
Is OTEZLA safe and effective for use in pediatric patients?No, the safety and effectiveness of OTEZLA in pediatric patients less than 18 years of age have not been established.
Is OTEZLA safe for use in geriatric patients?According to clinical trials, there were no overall differences in the safety profile of geriatric patients ≥ 65 years of age and younger adult patients < 65 years of age. However, because patients 65 years of age or older may be at a higher risk of complications such as volume depletion or hypotension from severe diarrhea, nausea, or vomiting, monitor geriatric patients closely for such complications.
Is dosage adjustment needed for OTEZLA in patients with renal impairment?While no dosage adjustment is needed in patients with mild or moderate renal impairment, the dosage of OTEZLA should be reduced to 30 mg once daily in patients with severe renal impairment.
Is dosage adjustment needed for OTEZLA in patients with hepatic impairment?No, dosage adjustment is not necessary for OTEZLA in patients with moderate or severe hepatic impairment.
FAQ Data Source