Last Update: Jan, 11 2025

Dosage & Administration

For intravenous use only .

IndicationDoseInitial Infusion RateMaximum Infusion Rate (as tolerated)
PI300-600 mg/kg
(3-6 mL/kg)every 3-4 weeks
1 mg/kg/min (0.01 mL/kg/min)14 mg/kg/min (0.14 mL/kg/min)
Chronic ITP in adults2 g/kg (20 mL/kg), divided into 2 daily doses of 1 g/kg (10 mL/kg) given on 2 consecutive days1 mg/kg/min (0.01 mL/kg/min)8 mg/kg/min (0.08 mL/kg/min)
CIDP in adultsLoading dose: 2 g/kg (20 mL/kg), divided into 2 daily doses of 1 g/kg (10 mL/kg) given on 2 consecutive days
Maintenance dose: 1-2 g/kg (10-20 mL/kg) every 3 weeks divided in 2 doses given over 2 consecutive days
1 mg/kg/min (0.01 mL/kg/min)12 mg/kg/min (0.12 mL/kg/min)

Ensure that patients with pre-existing renal insufficiency are not volume depleted; discontinue PANZYGA if renal function deteriorates .

For patients at risk of renal dysfunction or thrombotic events, administer PANZYGA at the minimum dose and infusion rate practicable .

Panzyga Prescribing Information

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