What is the dosage of Prograf?

Prograf is available in 3 dosages, including 0.5 mg Cap, 1 mg Cap and 5 mg Cap

What does Prograf treat?

Prograf treats Atopic Dermatitis and Graft vs Host Disease

What is Prograf made of?

Prograf contains tacrolimus which is a undefined

How is Prograf administered?

Prograf is administered as a Oral Pill

Dosage & Administration Drug label

Prograf

(tacrolimus)

tacrolimus 0.5 MG Oral Capsule [Prograf]tacrolimus 1 MG Oral Capsule [Prograf]

View 1 more

BLACK BOX WARNING

Dosage & administration

Patient Population	Initial Oral Dosage (formulation)	Whole Blood Trough Concentration range
ADULT
Kidney Transplant
with azathioprine	0.2 mg/kg/day capsules divided in two doses, every 12 hours	Month 1-3: 7-20 ng/mL Month 4-12: 5-15 ng/mL
With MMF/IL-2 receptor antagonist	0.1 mg/kg/day capsules, divided in two doses, every 12 hours	Month 1-12: 4-11 ng/mL
Liver Transplant
With corticosteroids only	0.1-0.15 mg/kg/day capsules, divided in two doses, every 12 hours	Month 1-12: 5-20 ng/mL
Heart Transplant
With azathioprine or MMF	0.075 mg/kg/day capsules, divided in two doses, every 12 hours	Month 1-3: 10-20 ng/mL Month ≥ 4: 5-15 ng/mL
PEDIATRIC
Kidney Transplant
	0.3 mg/kg/day capsules, divided in two doses, every 12 hours	Month 1-12: 5-20 ng/mL
Liver Transplant
	0.15-0.2 mg/kg/day capsules 0.2 mg/kg/day, divided in two doses, every 12 hours	Month 1-12: 5-20 ng/mL
Heart Transplant	0.3 mg/kg/day* capsules divided in two doses, every 12 hours	Month 1-12: 5-20 ng/mL

MMF= Mycophenolate mofetil

*0.1 mg/kg/day if cell depleting induction treatment is administered

* Administer capsules consistently with or without food. ( 2.1)
* Therapeutic drug monitoring is recommended. ( 2.1, 2.6)
* Avoid eating grapefruit or drinking grapefruit juice. ( 2.1)
* See dosing adjustments for African-American patients ( 2.2), hepatic and renal impaired. ( 2.4, 2.5)
* For complete dosing information see the full prescribing information

drug label

Prograf prescribing information

Need to report a Prograf issue?

ONLINE FORMReport adverse event

Learn More

Can't find what you're looking for?

Our trained staff can help you:

Please note:

Access to a Field Reimbursement Manager (FRM) or Medical Science Liaison (MSL) varies by brand and may require talking with your rep first.
Samples are provided at the discretion of the brand.
We are unable to collect Protected Health Information (PHI), fill out forms, or submit them on your behalf.