What is the dosage of Prograf?

Prograf is available in 3 dosages, including 0.5 mg Cap, 1 mg Cap and 5 mg Cap

What does Prograf treat?

Prograf treats Atopic Dermatitis and Graft vs Host Disease

What is Prograf made of?

Prograf contains tacrolimus which is a undefined

How is Prograf administered?

Prograf is administered as a Oral Pill

Dosage & Administration Drug label

Prograf

(tacrolimus)

tacrolimus 0.5 MG Oral Capsule [Prograf]tacrolimus 1 MG Oral Capsule [Prograf]

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BLACK BOX WARNING

Dosage & administration


MMF= Mycophenolate mofetil
Patient Population		Initial Oral Dosage	Whole Blood Trough Concentration Range
ADULT
Kidney Transplant
With azathioprine		0.2 mg/kg/day capsules, divided in two doses, every 12 hours	Month 1-3: 7-20 ng/mL Month 4-12: 5-15 ng/mL
With MMF/IL-2 receptor antagonist		0.1 mg/kg/day capsules, divided in two doses, every 12 hours	Month 1-12: 4-11 ng/mL
Liver Transplant
With corticosteroids only		0.1-0.15 mg/kg/day capsules, divided in two doses, every 12 hours	Month 1-12: 5-20 ng/mL
Heart Transplant
With azathioprine or MMF		0.075 mg/kg/day capsules, divided in two doses, every 12 hours	Month 1-3: 10-20 ng/mL Month ≥ 4: 5-15 ng/mL
PEDIATRIC
Liver Transplant
	0.15-0.2 mg/kg/day capsules divided in two doses, every 12 hours		Month 1-12: 5-20 ng/mL

* Intravenous (IV) use recommended for patients who cannot tolerate oral formulations (capsules).
* Administer capsules consistently with or without food.
* Therapeutic drug monitoring is recommended.
* Avoid eating grapefruit or drinking grapefruit juice.
* See dosage adjustments for African-American patients , hepatic and renal impaired.
* For complete dosing information, see the full prescribing information.

drug label

Prograf prescribing information

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