What is the dosage of Xalkori?

Xalkori is available in 2 dosages, including 200 mg Cap and 250 mg Cap

What does Xalkori treat?

Xalkori treats Non-Small-Cell Lung Carcinoma

What is Xalkori made of?

Xalkori contains crizotinib which is a Kinase Inhibitor

How is Xalkori administered?

Xalkori is administered as a Oral Pill

What is Xalkori mechanism of action?

Xalkori mechanism of action is Cytochrome P450 2B6 Inhibitors, Cytochrome P450 3A Inhibitors, Organic Cation Transporter 1 Inhibitors, Organic Cation Transporter 2 Inhibitors, P-Glycoprotein Inhibitors or Receptor Tyrosine Kinase Inhibitors

Dosage & Administration Drug label Samples Prior authorization Financial assistance

Patient education

Xalkori

(crizotinib)

crizotinib 200 MG Oral Capsule [Xalkori]crizotinib 250 MG Oral Capsule [Xalkori]

NO BLACK BOX WARNING

Dosage & administration

* Metastatic NSCLC: The recommended dosage is 250 mg orally twice daily.
* Systemic ALCL: The recommended dosage is 280 mg/m2 orally twice daily based on body surface area.
* Unresectable IMT:
* Adult: The recommended dosage is 250 mg orally twice daily.
* Pediatric: The recommended dosage is 280 mg/m2 orally twice daily based on body surface area.

* See full prescribing information for dosage adjustments by indication for patients with moderate or severe hepatic impairment or severe renal impairment.

drug label

Xalkori prescribing information

Have more Xalkori questions?

Submit MSL Request

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Need to report a Xalkori issue?

ONLINE FORMReport adverse event

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samples

Request Xalkori samples

Online Sample Form

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prior authorization

Xalkori Prior authorization resources

Complete Letter of Medical Necessity

NOT PROVIDED BY BRANDCoverage Authorization Request

Coverage Authorization Appeals

Formulary Exception Letter

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Benefits investigation

Pfizer Oncology Together Form

Pfizer Oncology Together Form - Spanish

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Reimbursement help (FRM)

Receive Assistance from an FRM Regarding Reimbursement Information

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financial assistance

Xalkori Financial assistance options

Co-pay savings program

commercial only

Enroll in Patient Savings Program

HCP Office: Attest & Print Co-Pay Card

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

commercial only

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Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries

How to sign up

Typically HCP assisted enrollment (via form)

Foundation programs

under insured

no insurance

goverment insurance

65+

Pfizer Oncology Together Form

Pfizer Oncology Together Form - Spanish

Pfizer Patient Assistance Program

Pfizer Pledge Warranty Program

Pfizer Pledge Patient Warranty Claim Form

Pfizer Pledge Patient Declarations and Authorizations Form

Pfizer Pledge Physician Attestation Form

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.

How to sign up

Patients submit proof of out-of-pocket drug costs to charities for reimbursement

patient education

Xalkori Patient education