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Pharmacyclics LLC

Imbruvica

Oncology

Indications and Usage

1.1        Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

IMBRUVICA is indicated for the treatment of adult patients with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL).

1.2        Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma with 17p deletion

IMBRUVICA is indicated for the treatment of adult patients with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) with 17p deletion.

1.3        Waldenström’s Macroglobulinemia

IMBRUVICA is indicated for the treatment of adult patients with Waldenström’s macroglobulinemia (WM).

1.4        Chronic Graft versus Host Disease

IMBRUVICA is indicated for the treatment of adult and pediatric patients age 1 year and older with chronic graft-versus-host disease (cGVHD) after failure of one or more lines of systemic therapy.

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