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E.R. Squibb & Sons, L.L.C.

Orencia

Rheumatoid Arthritis

Indications and Usage

Adult Rheumatoid Arthritis

ORENCIA® is indicated for the treatment of adult patients with moderately to severely active rheumatoid arthritis (RA).

Polyarticular Juvenile Idiopathic Arthritis

ORENCIA is indicated for the treatment of patients 2 years of age and older with moderately to severely active polyarticular juvenile idiopathic arthritis (pJIA).

Psoriatic Arthritis

ORENCIA is indicated for the treatment of patients 2 years of age and older with active psoriatic arthritis (PsA).

Prophylaxis for Acute Graft versus Host Disease

ORENCIA is indicated for the prophylaxis of acute graft versus host disease (aGVHD), in combination with a calcineurin inhibitor and methotrexate, in adults and pediatric patients 2 years of age and older undergoing hematopoietic stem cell transplantation (HSCT) from a matched or 1 allele-mismatched unrelated-donor.

Limitations of Use

The concomitant use of ORENCIA with other potent immunosuppressants [e.g., biologic disease-modifying antirheumatic drugs (bDMARDs), Janus kinase (JAK) inhibitors] is not recommended.

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