Actemra

(tocilizumab)
0.9 ML tocilizumab 180 MG/ML Auto-Injector [Actemra]0.9 ML tocilizumab 180 MG/ML Prefilled Syringe [Actemra]
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Dosage & administration

For RA, pJIA and sJIA, ACTEMRA may be used alone or in combination with methotrexate: and in RA, other DMARDs may be used.

General Administration and Dosing Information

Rheumatoid Arthritis

Recommended Adult Intravenous Dosage:

When used in combination with DMARDs or as monotherapy the recommended starting dose is 4 mg per kg every 4 weeks followed by an increase to 8 mg per kg every 4 weeks based on clinical response.

Recommended Adult Subcutaneous Dosage:

Patients less than 100 kg weight162 mg administered subcutaneously every other week, followed by an increase to every week based on clinical response
Patients at or above 100 kg weight162 mg administered subcutaneously every week

Giant Cell Arteritis

Recommended Adult Intravenous Dosage:

The recommended dose is 6 mg per kg every 4 weeks in combination with a tapering course of glucocorticoids. ACTEMRA can be used alone following discontinuation of glucocorticoids.

Recommended Adult Subcutaneous Dosage:

The recommended dose is 162 mg given once every week as a subcutaneous injection, in combination with a tapering course of glucocorticoids.

A dose of 162 mg given once every other week as a subcutaneous injection, in combination with a tapering course of glucocorticoids, may be prescribed based on clinical considerations.

ACTEMRA can be used alone following discontinuation of glucocorticoids.

Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD)

Recommended Adult Subcutaneous Dosage:

The recommended dose of ACTEMRA for adult patients with SSc-ILD is 162 mg given once every week as a subcutaneous injection.

Polyarticular Juvenile Idiopathic Arthritis

Recommended Intravenous PJIA Dosage Every 4 Weeks
Patients less than 30 kg weight10 mg per kg
Patients at or above 30 kg weight8 mg per kg
Recommended Subcutaneous PJIA Dosage
Patients less than 30 kg weight162 mg once every three weeks
Patients at or above 30 kg weight162 mg once every two weeks

Systemic Juvenile Idiopathic Arthritis

Recommended Intravenous SJIA Dosage Every 2 Weeks
Patients less than 30 kg weight12 mg per kg
Patients at or above 30 kg weight8 mg per kg
Recommended Subcutaneous SJIA Dosage
Patients less than 30 kg weight162 mg every two weeks
Patients at or above 30 kg weight162 mg every week

Cytokine Release Syndrome

Recommended Intravenous CRS Dosage
Patients less than 30 kg weight12 mg per kg
Patients at or above 30 kg weight8 mg per kg
Alone or in combination with corticosteroids.

Coronavirus Disease 2019

The recommended dosage of ACTEMRA for adult patients with COVID-19 is 8 mg per kg administered by a 60-minute intravenous infusion.

Administration of Intravenous formulation


Administration of Subcutaneous formulation


Dose Modifications


drug label

Actemra prescribing information

Have more Actemra questions?

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Need to report an Actemra issue?

ONLINE FORM
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samples

Request Actemra samples

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prior authorization

Actemra Prior authorization resources

Complete Letter of Medical Necessity

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Coverage Authorization Request
Coverage Authorization Appeals
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Benefits investigation

Rheumatology Subsequent Verification Program (RSVP) Enrollment Form
Actemra Prescriber Service Form
Actemra Prescriber Service Form - Online
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Reimbursement help (FRM)

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Reimbursement help (FRM) resources
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financial assistance

Actemra Financial assistance options

Co-pay savings program

commercial only
Actemra Prescriber Service Form
Actemra Prescriber Service Form - Online
Enroll in Patient Savings Program
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Bridge program

commercial only
Actemra Prescriber Service Form
Actemra Prescriber Service Form - Online
ACT Fast Bridge Program
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Foundation programs

under insured
no insurance
goverment insurance
65+
Genentech Patient Assistance Foundation Prescriber Form
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patient education

Actemra Patient education

Getting started on Actemra

Instructions For Use: Rheumatoid Arthritis
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Instructions For Use: Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD)
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Instructions For Use: Giant Cell Arteritis (GCA)
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Instructions For Use: Polyarticular Juvenile Idiopathic Arthritis (PJIA)
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Instructions For Use: Systemic Juvenile Idiopathic Arthritis (SJIA)
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Instructions For Use: Cytokine Release Syndrome (CRS)
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NOT PROVIDED BY BRAND
Instructions For Use: Coronavirus Disease 2019 (COVID-19)

Patient toolkit

About Actemra: RA
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Actemra Treatment Options: RA
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Receiving Actemra IV Infusion: RA
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Patient Stories: RA
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Doctor Discussion Guide: RA
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Patient Brochure: RA
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Patient Brochure (Spanish): RA
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About Actemra: SSc-ILD
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Side Effects: SSc-ILD
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View How to Take Actemra: SSc-ILD
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Patient Resources: SSc-ILD
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Sign Up For Travel Pack & Sharps Container: SSc-ILD
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Patient Brochure: SSc-ILD
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About Actemra: GCA
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View How to Take Actemra: GCA
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Receiving Actemra Infusion: GCA
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Tips For Living With GCA
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Caregiver Resources
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Patient Resources: GCA
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