What is the dosage of Afinitor?

Afinitor is available in 7 dosages, including 10 mg Tab, 2 mg Tab, 2.5 mg Tab, 3 mg Tab, 5 mg Tab, 5 mg Tab and 7.5 mg Tab

What is Afinitor made of?

Afinitor contains everolimus which is a Kinase Inhibitor

How is Afinitor administered?

Afinitor is administered as a Oral Pill or Oral Suspension Tablet

What is Afinitor mechanism of action?

Afinitor mechanism of action is Cytochrome P450 2D6 Inhibitors, Cytochrome P450 3A4 Inhibitors, P-Glycoprotein Inhibitors, Protein Kinase Inhibitors or mTOR Inhibitors

Dosage & Administration Drug label Samples Prior authorization Financial assistance

Patient education

Afinitor

(everolimus)

everolimus 10 MG Oral Tablet [Afinitor]everolimus 2 MG Tablet for Oral Suspension [Afinitor]

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NO BLACK BOX WARNING

Dosage & administration

Do not combine AFINITOR and AFINITOR DISPERZ to achieve the total daily dose.

Modify the dose for patients with hepatic impairment or for patients taking drugs that inhibit or induce P-glycoprotein (P-gp) and CYP3A4.

Breast Cancer:

* 10 mg orally once daily.

NET:

* 10 mg orally once daily.

RCC:

* 10 mg orally once daily.

TSC-Associated Renal Angiomyolipoma:

* 10 mg orally once daily.

TSC-Associated SEGA:

* 4.5 mg/m2 orally once daily; adjust dose to attain trough concentrations of 5-15 ng/mL.

TSC-Associated Partial-Onset Seizures:

* 5 mg/m2 orally once daily; adjust dose to attain trough concentrations of 5-15 ng/mL.

Afinitor prescribing information

Have more Afinitor questions?

Submit MSL Request

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Need to report an Afinitor issue?

ONLINE FORMReport adverse event

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samples

Request Afinitor samples

NOT PROVIDED BY BRANDView Online Sample Form

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prior authorization

Afinitor Prior authorization resources

NOT PROVIDED BY BRANDComplete Letter of Medical Necessity

NOT PROVIDED BY BRANDCoverage Authorization Request

NOT PROVIDED BY BRANDComplete Coverage Authorization appeals

NOT PROVIDED BY BRANDCoverage Authorization Appeal

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Benefits investigation

NOT PROVIDED BY BRANDBenefits investigation resources

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Reimbursement help (FRM)

NOT PROVIDED BY BRANDReimbursement help (FRM) resources

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financial assistance

Afinitor Financial assistance options

Co-pay savings program

commercial only

Enroll in patient savings program - Oncology Indications

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

commercial only

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Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries

How to sign up

Typically HCP assisted enrollment (via form)

Foundation programs

under insured

no insurance

goverment insurance

65+

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.

How to sign up

Patients submit proof of out-of-pocket drug costs to charities for reimbursement

patient education

Afinitor Patient education

Getting started on Afinitor

NOT PROVIDED BY BRANDInstructions For Use - Seizure with Tuberous Sclerosis Complex

NOT PROVIDED BY BRANDInstructions For Use - SEGA with Tuberous Sclerosis Complex

NOT PROVIDED BY BRANDInstructions For Use - Renal Angiomyolipoma with Tuberous Sclerosis Complex

NOT PROVIDED BY BRANDInstructions for Use - Advanced HR+, HER-2 Negative Breast Cancer

NOT PROVIDED BY BRANDInstructions For Use - Advanced Renal Cell Carcinoma

NOT PROVIDED BY BRANDInstructions For Use - Advanced Pancreatic Neuroendocrine Tumor (NET)

NOT PROVIDED BY BRANDInstructions For Use - Progressive Nonfunctional GI and Lung Neuroendocrine Tumors (NET)

Patient toolkit

NOT PROVIDED BY BRANDNot Provided By Brand

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Please note:

Access to a Field Reimbursement Manager (FRM) or Medical Science Liaison (MSL) varies by brand and may require talking with your rep first.
Samples are provided at the discretion of the brand.
We are unable to collect Protected Health Information (PHI), fill out forms, or submit them on your behalf.

Afinitor

Dosage & administration

Most viewed Afinitor resources

drug label

Afinitor prescribing information

Have more Afinitor questions?

Need to report an Afinitor issue?

samples

Request Afinitor samples

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prior authorization

Afinitor Prior authorization resources

Benefits investigation

Reimbursement help (FRM)

financial assistance

Afinitor Financial assistance options

Co-pay savings program

Overview

Patient benefit

Patient eligibility

How to sign up

Bridge program

Overview

Patient benefit

Patient eligibility

How to sign up

Foundation programs

Overview

Patient benefit

Patient eligibility

How to sign up

patient education

Afinitor Patient education

Getting started on Afinitor

Patient toolkit

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