16 ML bevacizumab 25 MG/ML Injection [Avastin]4 ML bevacizumab 25 MG/ML Injection [Avastin]
NO BLACK BOX WARNING
Dosage & administration
Withhold for at least 28 days prior to elective surgery. Do not administer Avastin for 28 days following major surgery and until adequate wound healing.
Metastatic colorectal cancer
First-line non–squamous non–small cell lung cancer
* 15 mg/kg every 3 weeks with carboplatin and paclitaxel
Recurrent glioblastoma
* 10 mg/kg every 2 weeks
Metastatic renal cell carcinoma ( 2.5)
* 10 mg/kg every 2 weeks with interferon alfa
Persistent, recurrent, or metastatic cervical cancer
* 15 mg/kg every 3 weeks with paclitaxel and cisplatin, or paclitaxel and topotecan
Stage III or IV epithelial ovarian, fallopian tube or primary peritoneal cancer following initial surgical resection
* 15 mg/kg every 3 weeks with carboplatin and paclitaxel for up to 6 cycles, followed by 15 mg/kg every 3 weeks as a single agent, for a total of up to 22 cycles
Platinum-resistant recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer
* 10 mg/kg every 2 weeks with paclitaxel, pegylated liposomal doxorubicin, or topotecan given every week * 15 mg/kg every 3 weeks with topotecan given every 3 weeks
Platinum-sensitive recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer
* 15 mg/kg every 3 weeks with carboplatin and paclitaxel for 6-8 cycles, followed by 15 mg/kg every 3 weeks as a single agent * 15 mg/kg every 3 weeks with carboplatin and gemcitabine for 6-10 cycles, followed by 15 mg/kg every 3 weeks as a single agent
Hepatocellular Carcinoma
* 15 mg/kg after administration of 1,200 mg of atezolizumab every 3 weeks
Administer as an intravenous infusion after dilution. See full Prescribing Information for preparation and administration instructions and dosage modifications for adverse reactions
Most viewed Avastin resources
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eficacy, safety & testing
Avastin clinical details
Efficacy: Metastatic Colorectal Cancer (mCRC)
Safety Profile: Metastatic Colorectal Cancer (mCRC)
Dosing: Metastatic Colorectal Cancer (mCRC)
Mechanism of Action (MOA)
Efficacy: Non–Small Cell Lung Cancer (NSCLC)
Safety Profile: Non–Small Cell Lung Cancer (NSCLC)
Dosing: Non–Small Cell Lung Cancer (NSCLC)
Efficacy: Metastatic Kidney Cancer (mRCC)
Safety Profile: Metastatic Kidney Cancer (mRCC)
Dosing: Metastatic Kidney Cancer (mRCC)
Efficacy: Advanced Cervical Cancer (CC)
Safety Profile: Advanced Cervical Cancer (CC)
Dosing: Advanced Cervical Cancer (CC)
Efficacy: Ovarian Cancer (OC)
Safety Profile: Ovarian Cancer (OC)
Dosing: Ovarian Cancer (OC)
Efficacy: Recurrent Glioblastoma (GBM)
Safety Profile: Recurrent Glioblastoma (GBM)
Dosing: Recurrent Glioblastoma (GBM)
drug label
Avastin prescribing information
Have more Avastin questions?
Submit MSL Request
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Your request will be referred to the appropriate Genentech, Inc. medical professional, such as a Avastin pharmaceutical rep; Medical Science Liaison (MSL) or medical affairs.
Need to report an Avastin issue?
ONLINE FORMReport adverse event
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You can report a Avastin adverse event on MedWatch, the FDA's medical product safety reporting program for health professionals, patients and consumers.
prior authorization
Avastin Prior authorization resources
Complete Letter of Medical Necessity
NOT PROVIDED BY BRANDCoverage Authorization Request
Coverage Authorization Appeals
Patient Consent Form
Patient Consent Form - Spanish
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If available, these templates are provided by the brand to help you navigate insurance, especially with newer drugs.
Benefits investigation
Avastin Prescriber Service & Patient Consent Form
Avastin Prescriber Service Form - Online Portal
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Benefits investigations are conducted to determine whether a therapy is covered under a patient's insurance, if a prior authorization is required, and which specialty pharmacies are preferred.
Reimbursement help (FRM)
Receive Assistance from an FRM Regarding Reimbursement Information
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Some brands offer a field reimbursement manager who will work with your clinical staff and preferred pharmacy to help make sure patients don't fall through the cracks.
financial assistance
Avastin Financial assistance options
Co-pay savings program
commercial only
Avastin Prescriber Service & Patient Consent Form
Enroll in Patient Savings Program
Avastin Prescriber Service Form - Online Portal
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Overview
Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)
Patient benefit
A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max
Patient eligibility
Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance
How to sign up
Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form
Bridge program
commercial only
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Overview
Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)
Patient benefit
100% free (outside of insurance)
Patient eligibility
HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries
How to sign up
Typically HCP assisted enrollment (via form)
Foundation programs
under insured
no insurance
goverment insurance
65+
Avastin Prescriber Service & Patient Consent Form
Genentech Patient Foundation Application Form (1/2)
Genentech Patient Foundation Application Form (2/2) - Patient Consent Form
Avastin Prescriber Service Form - Online Portal
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Overview
Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned
Patient benefit
Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted
Patient eligibility
Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.
How to sign up
Patients submit proof of out-of-pocket drug costs to charities for reimbursement
patient education
Avastin Patient education
Getting started on Avastin
NOT PROVIDED BY BRANDInstructions For Use: Metastatic Colorectal Cancer (mCRC)
NOT PROVIDED BY BRANDInstructions For Use: Non–Small Cell Lung Cancer (NSCLC)
NOT PROVIDED BY BRANDInstructions For Use: Metastatic Kidney Cancer (mRCC)
NOT PROVIDED BY BRANDInstructions For Use: Advanced Cervical Cancer (CC)
NOT PROVIDED BY BRANDInstructions For Use: Ovarian Cancer (OC)
NOT PROVIDED BY BRANDInstructions For Use: Recurrent Glioblastoma (GBM)
Patient toolkit
About Avastin
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Patient Resources
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
About Avastin: Metastatic Colorectal Cancer (mCRC)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Side Effects: Metastatic Colorectal Cancer (mCRC)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Receiving Avastin: Metastatic Colorectal Cancer (mCRC)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
About Avastin: Non–Small Cell Lung Cancer (NSCLC)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Side Effects: Non–Small Cell Lung Cancer (NSCLC)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Receiving Avastin: Non–Small Cell Lung Cancer (NSCLC)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
About Avastin: Metastatic Kidney Cancer (mRCC)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Side Effects: Metastatic Kidney Cancer (mRCC)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Receiving Avastin: Metastatic Kidney Cancer (mRCC)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
About Avastin: Advanced Cervical Cancer (CC)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Side Effects: Advanced Cervical Cancer (CC)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Receiving Avastin: Advanced Cervical Cancer (CC)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
About Avastin: Ovarian Cancer (OC)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Side Effects: Ovarian Cancer (OC)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Receiving Avastin: Ovarian Cancer (OC)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
About Avastin: Recurrent Glioblastoma (GBM)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Side Effects: Recurrent Glioblastoma (GBM)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Receiving Avastin: Recurrent Glioblastoma (GBM)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
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Other resources brands publish to help support patients and caregivers.
people also ask
Avastin FAQs
FAQ Data Source
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