Avycaz(avibactam / ceftazidime)
NO BOXED WARNING

Dosage & Administration

Dosage of AVYCAZ in Adult Patients with Creatinine Clearance (CrCl) greater than 50 mL/min ( 2.1)
InfectionDoseFrequencyInfusion Time
cIAI*, cUTI including Pyelonephritis, and HABP/VABPAVYCAZ 2.5 grams (ceftazidime 2 grams and avibactam
0.5 grams)
Every 8 hours   2 hours
*Used in conjunction with metronidazole 0.5 g intravenously every 8 hours in adult cIAI patients

*Used in conjunction with metronidazole 10 mg/kg intravenously every 8 hours in pediatric cIAI patients

aIncludes full-term infants with PNA > 28 days and pre-term infants with corrected age > 28 days. Corrected age is calculated by subtracting the number of weeks born before 40 weeks of gestation from the postnatal age.

bIncludes neonates PNA ≤ 28 days and pre-term infants with corrected age ≤ 28 days.

GA = gestational age and PNA = postnatal age.


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