Dosage in Adult Patients ( 2.1, 2.3): | ||
Estimated Creatinine Clearance (CLcr) | Single Dose Regimen | Two-Dose Regimen |
30 mL/min and above or on regular hemodialysis | 1500 mg | 1000 mg followed one week later by 500 mg |
Less than 30 mL/min and not on regular hemodialysis | 1125 mg | 750 mg followed one week later by 375 mg |
Dosage in Pediatric Patients with CLcr 30 mL/min/1.73m2 and above ( 2.2) | |
Age Range | Dosage (Single Dose Regimen) |
Birth to less than 6 years | 22.5 mg/kg (maximum of 1500 mg) |
6 to less than 18 years | 18 mg/kg (maximum of 1500 mg) |