What is the dosage of Herceptin?

Herceptin is available in 2 dosages, including 150 mg Injection and 21 mg/ml Sol

What does Herceptin treat?

Herceptin treats Breast Neoplasms and Gastrointestinal Neoplasms

What is Herceptin made of?

Herceptin contains trastuzumab which is a HER2/neu Receptor Antagonist

How is Herceptin administered?

Herceptin is administered as a Injectable

What is Herceptin mechanism of action?

Herceptin mechanism of action is HER2/Neu/cerbB2 Antagonists

Dosage & Administration Drug label Prior authorization Financial assistance

Patient education

Herceptin

(trastuzumab)

trastuzumab 150 MG Injection [Herceptin]trastuzumab 21 MG/ML Injectable Solution [Herceptin]

BLACK BOX WARNING

Dosage & administration

For intravenous (IV) infusion only. Do not administer as an IV push or bolus.

Do not substitute Herceptin (trastuzumab) for or with ado-trastuzumab emtansine.

Perform HER2 testing using FDA-approved tests by laboratories with demonstrated proficiency.

Adjuvant Treatment of HER2-Overexpressing Breast Cancer

Administer at either:

* Initial dose of 4 mg/kg over 90 minute IV infusion, then 2 mg/kg over 30 minute IV infusion weekly for 12 weeks (with paclitaxel or docetaxel) or 18 weeks (with docetaxel/carboplatin). One week after the last weekly dose of Herceptin, administer 6 mg/kg as an IV infusion over 30–90 minutes every three weeks to complete a total of 52 weeks of therapy, or
* Initial dose of 8 mg/kg over 90 minutes IV infusion, then 6 mg/kg over 30–90 minutes IV infusion every three weeks for 52 weeks.

Metastatic HER2-Overexpressing Breast Cancer

* Initial dose of 4 mg/kg as a 90 minute IV infusion followed by subsequent weekly doses of 2 mg/kg as 30 minute IV infusions.

Metastatic HER2-Overexpressing Gastric Cancer ( 2.2)

* Initial dose of 8 mg/kg over 90 minutes IV infusion, followed by 6 mg/kg over 30 to 90 minutes IV infusion every 3 weeks.

drug label

Herceptin prescribing information

Have more Herceptin questions?

Submit MSL Request

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Need to report a Herceptin issue?

ONLINE FORMReport adverse event

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prior authorization

Herceptin Prior authorization resources

Complete Letter of Medical Necessity

NOT PROVIDED BY BRANDCoverage Authorization Request

Coverage Authorization Appeals

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Benefits investigation

Prescriber Service & Patient Consent Form

Prescriber Service Form - Online Portal

Patient Consent Form - English

Patient Consent Form - Spanish

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Reimbursement help (FRM)

Receive Assistance from an FRM Regarding Reimbursement Information

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financial assistance

Herceptin Financial assistance options

Co-pay savings program

commercial only

Prescriber Service & Patient Consent Form

Prescriber Service Form - Online Portal

Patient Consent Form - English

Patient Consent Form - Spanish

Enroll in Patient Savings Program

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

commercial only

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Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries

How to sign up

Typically HCP assisted enrollment (via form)

Foundation programs

under insured

no insurance

goverment insurance

65+

Prescriber Service & Patient Consent Form

Prescriber Service Form - Online Portal

Patient Consent Form - English

Patient Consent Form - Spanish

Genentech Prescriber Foundation Form

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.

How to sign up

Patients submit proof of out-of-pocket drug costs to charities for reimbursement

patient education

Herceptin Patient education

Getting started on Herceptin

NOT PROVIDED BY BRANDInstructions for Use: Early Breast Cancer

NOT PROVIDED BY BRANDInstructions for Use: Metastatic Breast Cancer

NOT PROVIDED BY BRANDInstructions For Use: Stomach Cancer