Ilaris

(canakinumab)
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Dosage & Administration

• CAPS: Recommended weight-based dosage is:

  - For patients > 40 kg: 150 mg subcutaneously, every 8 weeks

  - For patients ≥ 15 kg and < 40 kg: 2 mg/kg subcutaneously, every 8 weeks. For pediatric patients 15 kg to 40 kg with an inadequate response, the dose can be increased to 3 mg/kg.

• TRAPS, HIDS/MKD, and FMF: Recommended weight-based dosage is:

  - For patients > 40 kg: Starting dosage is 150 mg subcutaneously every 4 weeks. The dosage can be increased to 300 mg every 4 weeks if the clinical response is not adequate.

  - For patients ≤ 40 kg: Starting dosage is 2 mg/kg subcutaneously every 4 weeks. The dosage can be increased to 4 mg/kg every 4 weeks if the clinical response is not adequate.

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