Kyprolis and Dexamethasone (Kd) or Kyprolis, Daratumumab and Dexamethasone (DKd) or Kyprolis, Daratumumab and hyaluronidase-fihj and Dexamethasone (DKd)
20/70 mg/m2 once weekly
30 minutes
Kyprolis and Dexamethasone (Kd) or Kyprolis, Daratumumab and Dexamethasone (DKd) or Kyprolis, Daratumumab and hyaluronidase-fihj and Dexamethasone (DKd) or Kyprolis, Isatuximab and Dexamethasone (Isa-Kd) or Kyprolis Monotherapy
20/56 mg/m2 twice weekly
30 minutes
Kyprolis, Lenalidomide and Dexamethasone (KRd) or Kyprolis Monotherapy
20/27 mg/m2 twice weekly
10 minutes
eficacy, safety & testing
Kyprolis clinical details
Mechanism of Action (MOA)
Clinical Trial: DKd vs Kd
Efficacy: DKd vs Kd
Safety Profile: DKd vs Kd
Clinical Trial: Kd Once Weekly
Efficacy: Kd Once Weekly
Safety Profile: Kd Once Weekly
Clinical Trial: Kd vs Vd
Efficacy: Kd vs Vd
Efficacy (Results by Patient Type): Kd vs Vd
Safety Profile: Kd vs Vd
Clinical Trial: KRd vs Rd
Efficacy: KRd vs Rd
Efficacy (Results by Patient Type): KRd vs Rd
Safety Profile: KRd vs Rd
Dosing: DKd
Dosing: Kd Once Weekly
Dosing: Kd Twice Weekly
Dosing: KRd
Administration and Dose Modifications
drug label
Kyprolis prescribing information
Have more Kyprolis questions?
Submit MSL Request
Learn More
Your request will be referred to the appropriate Onyx Pharmaceuticals, Inc. medical professional, such as a Kyprolis pharmaceutical rep; Medical Science Liaison (MSL) or medical affairs.
Need to report a Kyprolis issue?
ONLINE FORMReport adverse event
Learn More
You can report a Kyprolis adverse event on MedWatch, the FDA's medical product safety reporting program for health professionals, patients and consumers.
prior authorization
Kyprolis Prior authorization resources
Complete Letter of Medical Necessity
NOT PROVIDED BY BRANDCoverage Authorization Request
Coverage Authorization Appeals
Learn More
If available, these templates are provided by the brand to help you navigate insurance, especially with newer drugs.
Benefits investigation
Benefit Verification
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Benefits investigations are conducted to determine whether a therapy is covered under a patient's insurance, if a prior authorization is required, and which specialty pharmacies are preferred.
Reimbursement help (FRM)
Receive Assistance from an FRM Regarding Reimbursement Information
Learn More
Some brands offer a field reimbursement manager who will work with your clinical staff and preferred pharmacy to help make sure patients don't fall through the cracks.
financial assistance
Kyprolis Financial assistance options
Co-pay savings program
commercial only
Enroll in Patient Savings Program
Learn More
Overview
Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)
Patient benefit
A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max
Patient eligibility
Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance
How to sign up
Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form
Bridge program
commercial only
Learn More
Overview
Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)
Patient benefit
100% free (outside of insurance)
Patient eligibility
HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries
How to sign up
Typically HCP assisted enrollment (via form)
Foundation programs
under insured
no insurance
goverment insurance
65+
Amgen Safety Net Foundation Patient Assistance Program
Learn More
Overview
Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned
Patient benefit
Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted
Patient eligibility
Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.
How to sign up
Patients submit proof of out-of-pocket drug costs to charities for reimbursement
patient education
Kyprolis Patient education
Getting started on Kyprolis
NOT PROVIDED BY BRANDInstructions For Use: Relapsed or Refractory Multiple Myeloma
Patient toolkit
About Kyprolis
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Side Effects
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Receiving Kyprolis
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Patient Stories
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Patient Resources
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Patient Brochure
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Patient Lab Results Tracker
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Learn More
Other resources brands publish to help support patients and caregivers.
people also ask
Kyprolis FAQs
FAQ Data Source
We receive information directly from the FDA and PrescriberPoint is updated as frequently as change are made available
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Please note:
Access to a Field Reimbursement Manager (FRM) or Medical Science Liaison (MSL) varies by brand and may require talking with your rep first.
Samples are provided at the discretion of the brand.
We are unable to collect Protected Health Information (PHI), fill out forms, or submit them on your behalf.
