What is the dosage of Kyprolis?

Kyprolis is available in 3 dosages, including 60 mg Injection, 30 mg Injection and 10 mg Injection

What is Kyprolis mechanism of action?

Kyprolis mechanism of action is Proteasome Inhibitors

Kyprolis Prescribing & Dosing Schedule

Q: What does Kyprolis treat?

Kyprolis treats Multiple Myeloma

Q: What is Kyprolis made of?

Kyprolis contains carfilzomib which is a Proteasome Inhibitor

Q: How is Kyprolis administered?

Kyprolis is administered as a Injectable

Last Update: Oct, 06 2024

Kyprolis(carfilzomib)

Kyprolis 10 MG Injection

NO BOXED WARNING

Dosage & Administration

* Hydrate prior to and following Kyprolis as needed.
* Premedicate prior to all Cycle 1 doses and if infusion-related reactions develop or reappear.
* The recommended dosing regimens are as follows. See Full Prescribing Information for additional dosage information.

Regimen	Dosage	Infusion Time
Kyprolis and Dexamethasone (Kd) or Kyprolis, Daratumumab and Dexamethasone (DKd) or Kyprolis, Daratumumab and hyaluronidase-fihj and Dexamethasone (DKd)	20/70 mg/m2 once weekly	30 minutes
Kyprolis and Dexamethasone (Kd) or Kyprolis, Daratumumab and Dexamethasone (DKd) or Kyprolis, Daratumumab and hyaluronidase-fihj and Dexamethasone (DKd) or Kyprolis, Isatuximab and Dexamethasone (Isa-Kd) or Kyprolis Monotherapy	20/56 mg/m2 twice weekly	30 minutes
Kyprolis, Lenalidomide and Dexamethasone (KRd) or Kyprolis Monotherapy	20/27 mg/m2 twice weekly	10 minutes

Get Your Patient on Kyprolis

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Kyprolis Prescribing Information

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Kyprolis Prior Authorization Resources

Most recent state uniform prior authorization forms

Verified: Sep 24, 2024Arizona - Uniform Prior Authorization Form

Verified: Sep 24, 2024Colorado - Uniform Prior Authorization Form

Verified: Sep 24, 2024Hawaii - Uniform Prior Authorization Form

Verified: Sep 24, 2024Illinois - Uniform Prior Authorization Form

Verified: Sep 24, 2024Indiana - Uniform Prior Authorization Form

Verified: Sep 24, 2024Louisiana - Uniform Prior Authorization Form

Verified: Sep 24, 2024Minnesota - Uniform Prior Authorization Form

Verified: Sep 24, 2024New Hampshire - Uniform Prior Authorization Form

Verified: Sep 24, 2024New Mexico - Uniform Prior Authorization Form

Verified: Sep 24, 2024Oregon - Uniform Prior Authorization Form

Verified: Sep 24, 2024Texas - Uniform Prior Authorization Form

Verified: Oct 05, 2024Washington - Uniform Prior Authorization Form

Verified: Oct 05, 2024Wisconsin - Uniform Prior Authorization Form

Benefit Verification & PA Form

Coverage Authorization Appeals

Coverage Authorization Request

Complete Letter of Medical Necessity

Benefits investigation

Benefit Verification & PA Form

Reimbursement help (FRM)

Receive Assistance from an FRM Regarding Reimbursement Information

Kyprolis Financial Assistance Options

Copay savings program

Enroll in Patient Savings Program

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form