Dosage & Administration
BLACK BOX WARNING
Dosage & administration
* Verify pregnancy status in females of reproductive potential before starting Methotrexate Injection. ( 2.1, 4, 5.1)
* Neoplastic diseases: Refer to the prescribing information for disease specific dosing recommendations. Follow guidelines for high-dose regimens. ( 2.2, 2.3, 2.4, 2.5, 2.6, 2.7, 2.8, 2.9)
* RA: Recommended starting dosage of 7.5 mg once weekly intramuscularly; adjust dose to achieve an optimal response. ( 2.10)
* pJIA: Recommended starting dosage of 10 mg/m2 once weekly subcutaneously or intramuscularly; adjust dose to achieve an optimal response. ( 2.11)
* Psoriasis: Recommended dosage of 10 mg to 25 mg once weekly intramuscularly or intravenously; adjust dose to achieve optimal response. Once achieved, reduce to lowest possible dosage. ( 2.12)
Methotrexate prescribing information
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people also ask
How is the dosage of Methotrexate?
is available in 3 dosages, including 25 mg/ml Injection 10 ml, 25 mg/ml Injection 2 ml and 25 mg/ml Injection 40 ml
What does Methotrexate treat?
treats Juvenile Arthritis, Rheumatoid Arthritis, Breast Neoplasms, Choriocarcinoma, Crohn Disease, Esophageal Neoplasms, Hydatidiform Mole, Leukemia, Lung Neoplasms, Mycosis Fungoides, Psoriasis, Osteosarcoma, Stomach Neoplasms and Testicular Neoplasms
What is Methotrexate made of?
contains methotrexate which is a Folate Analog Metabolic Inhibitor
How Is Methotrexate Administered?
is administered as a Injectable
What Are The Methotrexate Mechanism Of Action?
mechanism of action is Folic Acid Metabolism Inhibitors
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