Rhophylac

(Rho(D) immune globulin)
2 ML Rho(D) immune globulin, human 750 UNT/ML Prefilled Syringe [Rhophylac]

Dosage & administration

DO NOT confuse micrograms (mcg) with International Units (IU) when calculating the dose. Miscalculations could result in overdose or underdose

Suppression of Rh Isoimmunization (IV or IM administration only)

IndicationTimingDose * (1 mcg = 5 IU)
Rh-incompatible Pregnancy:mcgIU

Routine antepartum prophylaxisWeek 28-30 of pregnancy300 mcg1500 IU
Postpartum prophylaxis (required only if the newborn is Rh(D)-positive, or of unknown status)Within 72 hours of birth300 mcg †1500 IU
Obstetric complications/invasive proceduresWithin 72 hours of complication / procedure300 mcg †1500 IU
Excessive fetomaternal hemorrhage (>15 mL fetal RBCs)Within 72 hours of complication300 mcg plus:
20 mcg per mL RhD-positive fetal RBCs in excess of 15 mL if excess transplacental bleeding is quantified, or
An additional 300 mcg if excess transplacental bleeding cannot be quantified
1500 IU plus:
100 IU per mL RhD- positive fetal RBCs in excess of 15 mL if excess transplacental bleeding is quantified, or
An additional 1500 IU if excess transplacental bleeding cannot be quantified
Incompatible transfusionsWithin 72 hours of exposure20 mcg per 2 mL transfused Rh(D)-positive whole blood or per 1 mL Rh(D)- positive RBCs100 IU per 2 mL transfused Rh(D)- positive whole blood or per 1 mL Rh(D)- positive RBCs

Treatment of ITP (IV administration only)

Dose (mcg)Rate of administration
50 mcg per kg body weight2 mL per 15 to 60 seconds

drug label

Rhophylac prescribing information

PubMed™ | Rhophylac

Rhophylac PubMed™ News

patient education

Rhophylac patient education

To share resource; ask patient to:
1.Pull out phone
2.Open camera
3.Scan QR code with camera
4.Tap link

Patient toolkit

Patient Brochure
ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link
Learn More

people also ask

Rhophylac FAQs

How is the dosage of Rhophylac?Rhophylac is available in 1 dosages, including 750 unt/ml Prefilled Syringe 2 ml
What does Rhophylac treat?Rhophylac treats Rh Isoimmunization and Idiopathic Thrombocytopenic Purpura
What is Rhophylac made of?Rhophylac contains Rho(D) immune globulin which is a Human Immunoglobulin G
How Is Rhophylac Administered?Rhophylac is administered as a Injectable
What Are The Rhophylac Mechanism Of Action?Rhophylac mechanism of action is Endogenous Antigen Neutralization
FAQ Data Source