Saxenda

Question 1

Is SAXENDA® safe during pregnancy?

Accepted Answer

SAXENDA® is contraindicated during pregnancy as weight loss offers no benefit and may harm the fetus. There's limited data on its use in pregnant women.

Question 2

What do animal studies reveal about liraglutide's effects during pregnancy?

Accepted Answer

Animal studies have shown increased adverse effects on embryofetal development due to liraglutide exposure during pregnancy, indicating potential harm.

Question 3

Are there data on the use of SAXENDA® during lactation?

Accepted Answer

There's no data on the presence of liraglutide in human milk, but it was detected in lactating rat milk. Consider breastfeeding benefits and potential risks of SAXENDA® for both mother and infant.

Question 4

Is SAXENDA® approved for pediatric use?

Accepted Answer

SAXENDA® is approved for pediatric patients aged 12 years and older with obesity, supported by clinical trials. However, some adverse events were reported in these trials.

Question 5

How does SAXENDA® perform in geriatric patients?

Accepted Answer

In clinical trials, no significant differences were observed in safety or effectiveness between older and younger patients. However, caution is advised in the elderly.

Question 6

What precautions should be taken for patients with renal impairment using SAXENDA®?

Accepted Answer

Limited experience exists for SAXENDA® in patients with renal impairment. There have been reports of renal failure, necessitating caution in this population.

Question 7

How about the use of SAXENDA® in patients with hepatic impairment?

Accepted Answer

Limited experience exists for SAXENDA® in patients with hepatic impairment, indicating caution in this patient population.

Question 8

Is SAXENDA® suitable for patients with pre-existing gastroparesis?

Accepted Answer

SAXENDA® has not been studied in patients with pre-existing gastroparesis.