Wakix Prescribing & Dosing Schedule

Q: What is the dosage of Wakix?

Wakix is available in 2 dosages, including 17.8 mg Tab and 4.45 mg Tab

Q: What does Wakix treat?

Wakix treats Sleep Wake Disorders

Q: What is Wakix made of?

Wakix contains pitolisant which is a Histamine-3 Receptor Antagonist/Inverse Agonist

Q: How is Wakix administered?

Wakix is administered as a Oral Pill

Q: What is Wakix mechanism of action?

Wakix mechanism of action is Cytochrome P450 3A4 Inducers, Histamine H3 Receptor Antagonists or Histamine H3 Receptor Inverse Agonists

Dosage & Administration Drug label Prior authorization Financial assistance Patient education People also ask

Wakix(pitolisant)

Wakix 4.45 MG Oral Tablet

NO BOXED WARNING

Dosage & Administration

* See Full Prescribing Information for complete dosage instructions
* Administer orally once daily in the morning upon wakening
* Dosage Recommendations:

Adults: EDS or Cataplexy
Week 1	Initiate with a dosage of 8.9 mg once daily
Week 2	Increase dosage to 17.8 mg once daily
Week 3	May increase to the maximum recommended dosage of 35.6 mg once daily

Pediatric Patients (6 years and older): EDS
Week 1	Initiate with a dosage of 4.45 mg once daily
Week 2	Increase dosage to 8.9 mg once daily
Week 3	Increase dosage to 17.8 mg once daily, the maximum recommended dosage for patients weighing <40 kg
Week 4	For patients weighing ≥40 kg, may increase to the maximum recommended dosage of 35.6 mg once daily

* Hepatic impairment :
* Moderate hepatic impairment (Child-Pugh Class B):
Adults: Initial dosage is 8.9 mg once daily. Titrate to a maximum dosage of 17.8 mg once daily after 14 days
Pediatric Patients: Initial dosage is 4.45 mg once daily. Titrate to 8.9 mg once daily after 14 days; for patients weighing ≥40 kg, may increase to 17.8 mg once daily after another 14 days

* Renal impairment (eGFR less than 60 mL/minute/1.73 m2) :
* Adults: Initial dosage is 8.9 mg once daily. Titrate to a maximum dosage of 17.8 mg once daily after 7 days
* Pediatric Patients: Initial dosage is 4.45 mg once daily. Titrate to 8.9 mg once daily after 7 days; for patients weighing ≥40 kg, may increase to 17.8 mg once daily after another 7 days
* End-stage renal disease (ESRD): Not recommended

* Poor Metabolizers of CYP2D6 :
* Adults: Maximum recommended dosage is 17.8 mg once daily
* Pediatric Patients: Maximum recommended dosage is 8.9 mg once daily for patients weighing <40 kg and 17.8 mg for patients weighing ≥40 kg

drug label

Wakix Prescribing Information

Contact Medical Science Liaison

Report Adverse Event

prior authorization

Wakix Prior Authorization Resources

Most recent state uniform prior authorization forms

Verified: Jun 26, 2024Arizona - Uniform Prior Authorization Form

Verified: Jun 26, 2024Colorado - Uniform Prior Authorization Form

Verified: Jun 26, 2024Hawaii - Uniform Prior Authorization Form

Verified: Jul 26, 2024Illinois - Uniform Prior Authorization Form

Verified: Jun 26, 2024Indiana - Uniform Prior Authorization Form

Verified: Jun 26, 2024Louisiana - Uniform Prior Authorization Form

Verified: Jun 26, 2024Minnesota - Uniform Prior Authorization Form

Verified: Jun 26, 2024New Hampshire - Uniform Prior Authorization Form

Verified: Jun 26, 2024New Mexico - Uniform Prior Authorization Form

Verified: Jun 26, 2024Oregon - Uniform Prior Authorization Form

Verified: Jun 26, 2024Texas - Uniform Prior Authorization Form

Verified: Jul 07, 2024Washington - Uniform Prior Authorization Form

Verified: Jul 07, 2024Wisconsin - Uniform Prior Authorization Form

Benefits investigation

Wakix Prescription Referral Form

financial assistance

Wakix Financial Assistance Options

Copay savings program

Enroll in Patient Savings Program

Wakix Prescription Referral Form

Learn More

Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

patient education

Wakix Patient Education

To share resource; ask patient to:

1.Pull out phone

2.Open camera

3.Scan QR code with camera

4.Tap link