IU, International Units; mcg, micrograms | ||
ITP (IV administration only) | ||
Dose IU | Dose mcg | Rate of Administration |
250 IU kg body weight | 50 mcg/kg body weight | Single injection over 3 to 5 minutes |
Suppression of Rh Isoimmunization (IV or IM administration only) | |||
Indication | Timing | Dose (IV or IM) | Dose (IV or IM) |
Pregnancy and other obstetric conditions | IU (international units) | mcg (micrograms) | |
Routine antepartum prophylaxis | 28-weeks gestation | 1,500 IU | 300 mcg |
Postpartum prophylaxis | Within 72 hours of delivery | 600 IU | 120 mcg |
Threatened abortion | Immediately | 1,500 IU | 300 mcg |
Amniocentesis and chorionic villus sampling before 34-weeks gestation | Immediately after procedure | 1,500 IU | 300 mcg |
Abortion, amniocentesis, or other manipulation after 34-weeks gestation | Within 72 hours | 600 IU | 120 mcg |
Incompatible transfusions or massive fetal hemorrhage | Within 72 hours of exposure | IV administration of 90 IU per 1 mL transfused RBC or per 2 mL transfused whole blood | IV administration of 18 mcg per 1 mL transfused RBC or per 2 mL transfused whole blood |