Zemplar

(paricalcitol)
Zemplar 1 MCG Oral CapsuleZemplar 2 MCG Oral Capsule
NO BLACK BOX WARNING

Dosage & administration

 

Initial Dosage: CKD Stages 3 and 4
Adult: Baseline iPTH ≤ 500 pg/mL1 mcg orally daily or 2 mcg three times a week*
Adult: Baseline iPTH > 500 pg/mL 2 mcg orally daily or 4 mcg three times a week*
Pediatric: Ages 10 to 16 years1 mcg orally three times a week*
Dose Titration: CKD Stages 3 and 4
Adult: iPTH same, increased or decreased by < 30% relative to baseline Increase dose by 1 mcg daily or 2 mcg three times a week*
Adult: iPTH decreased by ≥ 30% and ≤ 60% relative to baseline Maintain dose
Adult: iPTH decreased by > 60% or iPTH < 60 pg/mL relative to baseline Decrease dose by 1 mcg daily or 2 mcg three times a week*
Pediatric: Ages 10 to 16 yearsIncrease each dose by 1 mcg three times a week every 4 weeks or decrease each dose by 1 mcg three times a week at any time based on iPTH, serum calcium and phosphorus levels.*
* Not more frequently than every other day when dosing three times a week.
Initial Dosage: CKD Stage 5
Adult Dose (micrograms) = baseline iPTH (pg/mL) divided by 80. Administer dose orally three times a week.*
Pediatric: Ages 10 to 16 yearsDose (micrograms) = baseline iPTH (pg/mL) divided by 120. Administer dose orally three times a week.*
Dose Titration: CKD Stage 5
Adult Dose in micrograms is based on most recent iPTH (pg/mL) divided by 80 with adjustments based on serum calcium and phosphorous levels. Dose three times a week.*
Pediatric: Ages 10 to 16 years Increase each dose by 1 mcg three times a week every 4 weeks or decrease each dose by 2 mcg three times a week at any time based on iPTH, serum calcium and phosphorus levels.*
* Not more frequently than every other day.

 

 

drug label

Zemplar prescribing information

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Zemplar patient education

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people also ask

Zemplar FAQs

How is the dosage of Zemplar?Zemplar is available in 2 dosages, including 1 mcg Cap and 2 mcg Cap
What does Zemplar treat?Zemplar treats Hyperparathyroidism
What is Zemplar made of?Zemplar contains paricalcitol which is a Vitamin D3 Analog
How Is Zemplar Administered?Zemplar is administered as a Oral Pill
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