Compare drug alternatives

Segluromet® Alternatives

Segluromet®(metformin hydrochloride)
Inpefa®(sotagliflozin)
Prescription Only
Segluromet is a medication that combines ertugliflozin and metformin to regulate blood sugar levels. Ertugliflozin aids the kidneys in removing glucose from the bloodstream, while...
Prescription Only
Inpefa is an oral tablet taken once daily, and it contains sotagliflozin. It can be used to lower the chances of cardiovascular death, hospitalization due to heart failure, and...
Dosage & Administration
Administration
Oral . Learn more.
Oral . Learn more.
Dosing
Maximum recommended dose is 7.5 mg ertugliflozin/1,000 mg metformin twice daily. Take twice daily with meals, with gradual dose escalation. Do not use in patients with an estimated glomerular filtration rate (eGFR) below 30 mL/minute/1.73 m2 . . Learn more.
200 mg daily and titrate to 400 mg as tolerated.. Learn more.
Latin Shorthand
Max dose: 7.5 mg ertugliflozin / 1000 mg metformin BID. Take with meals, gradual dose increase. Avoid if eGFR < 30 mL/min/1.73 m².. Learn more.
Take 200 mg qd, increase to 400 mg qd if tolerated.. Learn more.
Financial Assistance
Out-Of-Pocket Costs With Copay Card
Annual Cap
$583 per fill . Learn more.
$2,600. Learn more.
Assistance Expiration
12 uses. Learn more.
12/31/25. Learn more.
Generics
No lower-cost generic available
No lower-cost generic available
Physician Advisory
Adverse Reactions
Most common adverse reactions associated with ertugliflozin (incidence ≥5%) were female genital mycotic infections. Most common adverse reactions associated with metformin (incidence ≥5%) were diarrhea, nausea, vomiting, flatulence, abdominal discomfort, indigestion, asthenia, and headache. . Learn more.
Most common adverse reactions (incidence ≥ 5%) are urinary tract infection, volume depletion, diarrhea, and hypoglycemia. . Learn more.
Mechanism of Actions (MoA)
SGLT2 Inhibitors. Learn more.
SGLT2 Inhibitors. Learn more.
Special Populations