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Skyrizi® Alternatives
Skyrizi®(risankizumab) | Stelara®(ustekinumab) |
---|---|
Prescription Only | Prescription Only |
Dosage & Administration | |
Administration | |
Subcutaneous Injection. Learn more. | Intravenous Infusion or Subcutaneous Injection . Learn more. |
Dosing | |
150 mg at Week 0, Week 4, and every 12 weeks thereafter.. Learn more. | Single intravenous infusion using weight-based dosing: Recommended Dosage up to 55 kg: 260 mg. > 55 kg to 85 kg: 390 mg. > 85 kg: 520 mg. Maintenance dosing: SubQ 90 mg dose 8 weeks after the initial intravenous dose, then every 8 weeks thereafter.. Learn more. |
Latin Shorthand | |
150 mg Week 0, 4 then q12w. Learn more. | Single IV infusion w/ weight-based dosing: Up to 55 kg: 260mg 55 to 85 kg: 390mg 85 kg: 520mg. Maintenance dosing: SubQ 90mg 8 wks after initial IV dose, then q8wks thereafter.. Learn more. |
Adverse Reactions | |
Most common adverse reactions are:
• Plaque Psoriasis and Psoriatic Arthritis (≥ 1%): upper respiratory
infections, headache, fatigue, injection site reactions, and tinea infections.
• Crohn’s Disease (>3%):
o Induction: upper respiratory infections, headache, and arthralgia.
o Maintenance: arthralgia, abdominal pain, injection site reactions,
anemia, pyrexia, back pain, arthropathy, and urinary tract infection.
. Learn more. | Most common adverse reactions are:
• Psoriasis (≥3%): nasopharyngitis, upper respiratory tract infection, headache,
and fatigue.
• Crohn’s Disease, induction (≥3%): vomiting.
• Crohn’s Disease, maintenance (≥3%): nasopharyngitis, injection site erythema,
vulvovaginal candidiasis/mycotic infection, bronchitis, pruritus, urinary tract
infection, and sinusitis.
• Ulcerative colitis, induction (≥3%): nasopharyngitis
• Ulcerative colitis, maintenance (≥3%): nasopharyngitis, headache, abdominal
pain, influenza, fever, diarrhea, sinusitis, fatigue, and nausea . Learn more. |
Financial Assistance | |
Out-Of-Pocket Costs With Copay Card | |
$5. Learn more. | $5. Learn more. |
Annual Cap | |
$6,000. Learn more. | |
Assistance Expiration | |
End of each calendar year (subject to change or discontinuation without notice). Learn more. | |
Generics | |
No lower-cost generic available | No lower-cost generic available |
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