Compare drug alternatives

Synjardy® Alternatives

Synjardy®(metformin hydrochloride)
Inpefa®(sotagliflozin)
Prescription Only
Synjardy is a medication that combines empagliflozin and metformin, both of which are oral drugs designed to regulate blood sugar levels. Empagliflozin functions by assisting the...
Prescription Only
Inpefa is an oral tablet taken once daily, and it contains sotagliflozin. It can be used to lower the chances of cardiovascular death, hospitalization due to heart failure, and...
Dosage & Administration
Administration
Oral . Learn more.
Oral . Learn more.
Dosing
Take orally twice daily with meals, with gradual dosage escalation to reduce the gastrointestinal side effects due to metformin.. Learn more.
200 mg daily and titrate to 400 mg as tolerated.. Learn more.
Latin Shorthand
Take PO BID with meals, titrate dose gradually to mitigate metformin GI SE.. Learn more.
Take 200 mg qd, increase to 400 mg qd if tolerated.. Learn more.
Financial Assistance
Out-Of-Pocket Costs With Copay Card
Annual Cap
$175 per month . Learn more.
$2,600. Learn more.
Assistance Expiration
12/31/25. Learn more.
Generics
No lower-cost generic available
No lower-cost generic available
Physician Advisory
Adverse Reactions
Most common adverse reactions associated with empagliflozin (5% or greater incidence) were urinary tract infection and female genital mycotic infections. Most common adverse reactions associated with metformin (>5%) are diarrhea, nausea/vomiting, flatulence, abdominal discomfort, indigestion, asthenia, and headache.. Learn more.
Most common adverse reactions (incidence ≥ 5%) are urinary tract infection, volume depletion, diarrhea, and hypoglycemia. . Learn more.
Mechanism of Actions (MoA)
SGLT2 Inhibitors. Learn more.
SGLT2 Inhibitors. Learn more.
Special Populations