Dupixent

(dupilumab)
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Dosage & Administration

Atopic Dermatitis
Dosage in Adults :

Dosage in Pediatric Patients 6 Months to 5 Years of Age :

Body WeightInitial and Subsequent Dosage
5 to less than 15 kg200 mg (one 200 mg injection) every 4 weeks (Q4W)
15 to less than 30 kg300 mg (one 300 mg injection) every 4 weeks (Q4W)

Dosage in Pediatric Patients 6 Years to 17 Years of Age :

Body WeightInitial Loading DoseSubsequent Dosage *

15 to less than 30 kg600 mg (two 300 mg injections)300 mg Q4W
30 to less than 60 kg400 mg (two 200 mg injections)200 mg Q2W
60 kg or more600 mg (two 300 mg injections)300 mg Q2W

Asthma
Dosage in Adult and Pediatric Patients 12 Years and Older :

Initial Loading DoseSubsequent Dosage
400 mg (two 200 mg injections)200 mg every 2 weeks (Q2W)
Or
600 mg (two 300 mg injections)300 mg every 2 weeks (Q2W)
Dosage for patients with oral corticosteroid-dependent asthma or with co-morbid moderate-to-severe atopic dermatitis or adults with co-morbid chronic rhinosinusitis with nasal polyps
600 mg (two 300 mg injections)300 mg every 2 weeks (Q2W)

Dosage in Pediatric Patients 6 to 11 Years of Age :

Body WeightInitial Dose and Subsequent Dosage
15 to less than 30 kg300 mg every four weeks (Q4W)
≥30 kg200 mg every other week (Q2W)

For pediatric patients 6 to 11 years old with asthma and co-morbid moderate-to-severe atopic dermatitis, follow the recommended dosage as per Table 2 which includes an initial loading dose.

Chronic Rhinosinusitis with Nasal Polyps :


Eosinophilic Esophagitis :

Body WeightRecommended Dosage in Adult and Pediatric Patients 1 Year and Older, Weighing At Least 15 kg
15 to less than 30 kg200 mg every other week (Q2W)
30 to less than 40 kg300 mg every other week (Q2W)
40 kg or more300 mg every week (QW)

Prurigo Nodularis :


Chronic Obstructive Pulmonary Disease :


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