Corticosteroid Hormone Receptor Agonists

Corticosteroid

Inflammation

Muscular Dystrophy, Duchenne

<section class="Section" data-sectioncode="34089-3"><a name="s_1100"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">The active ingredient in EMFLAZA is deflazacort (a corticosteroid).  Corticosteroids are adrenocortical steroids, both naturally occurring and synthetic.  The molecular formula for deflazacort is C<span class="Sub">25</span>H<span class="Sub">31</span>NO<span class="Sub">6</span>.  The chemical name for deflazacort is (11β,16β)-21-(acetyloxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, and the structure is:</p><p><img alt="The structural formula for EMFLAZA is deflazacort (a corticosteroid).  Corticosteroids are adrenocortical steroids, both naturally occurring and synthetic.  The molecular formula for deflazacort is C25H31NO6.  The chemical name for deflazacort is (11β,16β)-21-(acetyloxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione." src="emflaza-01.jpg"/></p><p>Deflazacort is a white to off white, odorless fine powder and has a molecular weight of 441.517.  Deflazacort is freely soluble in acetic acid and dichloromethane and soluble in methanol and acetone.</p><p>EMFLAZA for oral administration is available as an immediate-release tablet in strengths of 6, 18, 30 and 36 mg and an immediate-release oral suspension in a strength of 22.75 mg/mL.  Each tablet contains deflazacort and the following inactive ingredients: colloidal silicon dioxide, lactose monohydrate, magnesium stearate, and pre-gelatinized corn starch.  The oral suspension contains deflazacort and the following inactive ingredients: acetic acid, aluminum magnesium silicate, benzyl alcohol, carboxymethylcellulose sodium, polysorbate 80, purified water, and sorbitol.</p></section>

EMFLAZA

deflazacort 6 MG Oral Tablet

deflazacort 30 MG Oral Tablet

Emflaza

deflazacort 6 MG Oral Tablet [Emflaza]

deflazacort 30 MG Oral Tablet [Emflaza]

deflazacort 18 MG Oral Tablet

deflazacort 18 MG Oral Tablet [Emflaza]

deflazacort 36 MG Oral Tablet

deflazacort 36 MG Oral Tablet [Emflaza]

deflazacort 22.75 MG/ML Oral Suspension

deflazacort 22.75 MG/ML Oral Suspension [Emflaza]

deflazacort

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

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Cosentyx

Siliq

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Ilumya

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Aimovig

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Verzenio

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Xalkori

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Rinvoq

Entyvio

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Instructions For Use: Duchenne Muscular Dystrophy (DMD)

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