Insulin Analog

<section class="Section" data-sectioncode="34089-3"><a name="i4i_description_id_b51c8345-1819-492b-aaf7-ee9ecbea8b34"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">Insulin detemir is a long-acting recombinant human insulin analog produced by a process that includes expression of recombinant DNA in <span class="Italics">Saccharomyces cerevisiae</span> followed by chemical modification. </p><p>Insulin detemir differs from human insulin in that the amino acid threonine in position B30 has been omitted, and a C14 fatty acid chain has been attached to the amino acid B29. Insulin detemir has a molecular formula of C<span class="Sub">267</span>H<span class="Sub">402</span>O<span class="Sub">76</span>N<span class="Sub">64</span>S<span class="Sub">6</span> and a molecular weight of 5.917 kDa. It has the following structure:</p><p><span class="Bold">Figure 1: Structural Formula of Insulin Detemir</span></p><div class="Figure"><a name="id1028"></a><img alt="Levemir Chemical Structure.jpg" src="aa947266-e27c-432b-8e04-c36168d24ddb-01.jpg"/></div><p>LEVEMIR (insulin detemir) injection is a clear, colorless, aqueous, neutral sterile solution for subcutaneous use.  Each milliliter of LEVEMIR contains 100 units insulin detemir, dibasic sodium phosphate (0.71 mg), glycerin (16 mg), metacresol (2.06 mg), phenol (1.8 mg), sodium chloride (1.17 mg), zinc (65.4 mcg), and Water for Injection, USP. Hydrochloric acid and/or sodium hydroxide may be added to adjust pH.  LEVEMIR has a pH of approximately 7.4. </p></section>

Levemir

insulin detemir

insulin detemir 100 UNT/ML Injectable Solution

insulin detemir 100 UNT/ML Injectable Solution [Levemir]

3 ML insulin detemir 100 UNT/ML Pen Injector

3 ML insulin detemir 100 UNT/ML Pen Injector [Levemir]

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Instructions For Use (Vial): Diabetes 

Instructions For Use (Flex Pen): Diabetes 