Leukemia, Lymphoid

Leukemia, Myeloid

<section class="Section" data-sectioncode="34089-3"><a name="Section_11"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">SPRYCEL (dasatinib) is a kinase inhibitor. The chemical name for dasatinib is N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide, monohydrate. The molecular formula is C<span class="Sub">22</span>H<span class="Sub">26</span>ClN<span class="Sub">7</span>O<span class="Sub">2</span>S • H<span class="Sub">2</span>O, which corresponds to a formula weight of 506.02 (monohydrate). The anhydrous free base has a molecular weight of 488.01. Dasatinib has the following chemical structure:</p><div class="Figure"><a name="id2526"></a><img alt="dasatinib-struct.jpg" src="dasatinib-struct.jpg"/></div><p>Dasatinib is a white to off-white powder. The drug substance is insoluble in water and slightly soluble in ethanol and methanol.</p><p>SPRYCEL tablets are white to off-white, biconvex, film-coated tablets containing dasatinib, with the following inactive ingredients: lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, hydroxypropyl cellulose, and magnesium stearate. The tablet coating consists of hypromellose, titanium dioxide, and polyethylene glycol. </p></section>

SPRYCEL

dasatinib 140 MG Oral Tablet

dasatinib 140 MG Oral Tablet [Sprycel]

dasatinib 80 MG Oral Tablet

dasatinib 80 MG Oral Tablet [Sprycel]

dasatinib

dasatinib 20 MG Oral Tablet

dasatinib 50 MG Oral Tablet

dasatinib 70 MG Oral Tablet

Sprycel

dasatinib 20 MG Oral Tablet [Sprycel]

dasatinib 50 MG Oral Tablet [Sprycel]

dasatinib 70 MG Oral Tablet [Sprycel]

dasatinib 100 MG Oral Tablet

dasatinib 100 MG Oral Tablet [Sprycel]

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event 

Prescribing Information

Medication Guide 

Submit MSL Request 

Pharmacy List 

Billing & Coding Guide 

Formulary Information

Reimbursement Information

Sprycel Enrollment Form 

Sprycel Enrollment Form - Spanish 

My BMS Cases: Access Online Portal 

Coverage Authorization Request 

Coverage Authorization Appeals

Commercial Claim Denial Appeal/Redetermination Letter

Medically Unlikely Edit (MUE) Appeal Letter

Letter of Medical Necessity 

Other HCP Resources - Forms 

Enroll in Patient Savings Program 

30 Day Trial Offer Card 

About Sprycel: Adult Ph+CML 

Taking Sprycel: Adult Ph+CML 

Side Effects: Adult Ph+CML 

Doctor Discussion Tips: Adult Ph+CML 

About Sprycel: Pediatric Ph+ CML 

Taking Sprycel: Pediatric Ph+ CML 

Side Effects:  Pediatric Ph+ CML 

Patient Resources 

Patient Stories 

Sprycel Support 

Instructions For Use: Adult Ph+ CML 

Instructions For Use: Pediatric Ph+ CML