What is the dosage of Prograf?

Prograf is available in 3 dosages, including 0.5 mg Cap, 1 mg Cap and 5 mg Cap

What does Prograf treat?

Prograf treats Atopic Dermatitis and Graft vs Host Disease

What is Prograf made of?

Prograf contains tacrolimus which is a undefined

How is Prograf administered?

Prograf is administered as a Oral Pill

Dosage & Administration Drug label

Prograf

(tacrolimus)

tacrolimus 0.5 MG Oral Capsule [Prograf]tacrolimus 1 MG Oral Capsule [Prograf]

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BLACK BOX WARNING

Dosage & administration

* Intravenous (IV) use recommended for patients who cannot tolerate oral formulations (capsules). ( 2.1, 2.2)
* Administer capsules consistently with or without food. ( 2.1)
* Therapeutic drug monitoring is recommended. ( 2.1, 2.6)
* Avoid eating grapefruit or drinking grapefruit juice. ( 2.1)
* See dosage adjustments for African-American patients ( 2.2), hepatic and renal impaired. ( 2.4, 2.5)
* For complete dosing information, see the full prescribing information.

ADULT
Patient Population	Initial Oral Dosage (formulation)	Whole Blood Trough Concentration Range
Kidney Transplant
With azathioprine	0.2 mg/kg/day capsules, divided in two doses, every 12 hours	Month 1 to 3: 7 to 20 ng/mL Month 4 to 12: 5 to 15 ng/mL
With MMF/IL-2 receptor antagonist	0.1 mg/kg/day capsules, divided in two doses, every 12 hours	Month 1 to 12: 4 to 11 ng/mL
Liver Transplant
With corticosteroids only	0.1 to 0.15 mg/kg/day capsules, divided in two doses, every 12 hours	Month 1 to 12: 5 to 20 ng/mL
Heart Transplant
With azathioprine or MMF	0.075 mg/kg/day capsules, divided in two doses, every 12 hours	Month 1 to 3: 10 to 20 ng/mL Month ≥ 4: 5 to 15 ng/mL
PEDIATRIC
Patient Population	Initial Oral Dosage (formulation)	Whole Blood Trough Concentration Range
Liver Transplant
	0.15 to 0.2 mg/kg/day capsules divided in two doses, every 12 hours	Month 1 to 12: 5 to 20 ng/mL
MMF= Mycophenolate mofetil

drug label

Prograf prescribing information

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