Kinase Inhibitor

Kinase Inhibitors

Breast Neoplasms

<section class="Section" data-sectioncode="34089-3"><a name="s62"></a><a name="section-9"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">Abemaciclib is a kinase inhibitor for oral administration. It is a white to yellow powder with the empirical formula C<span class="Sub">27</span>H<span class="Sub">32</span>F<span class="Sub">2</span>N<span class="Sub">8</span> and a molecular weight 506.59.</p><p>The chemical name for abemaciclib is 2-Pyrimidinamine, <span class="Italics">N</span>-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1<span class="Italics">H</span>-benzimidazol-6-yl]-. Abemaciclib has the following structure:</p><div class="Figure"><a name="f01"></a><img alt="Abemaciclib Structure
" src="verzenio-pi-chem-struct-v1.jpg"/></div><p>VERZENIO (abemaciclib) tablets are provided as immediate-release oval white, beige, or yellow tablets. Inactive ingredients are as follows: Excipients—microcrystalline cellulose 102, microcrystalline cellulose 101, lactose monohydrate, croscarmellose sodium, sodium stearyl fumarate, silicon dioxide. Color mixture ingredients—polyvinyl alcohol, titanium dioxide, polyethylene glycol, talc, iron oxide yellow, and iron oxide red.</p></section>

Verzenio

abemaciclib

abemaciclib 100 MG Oral Tablet

abemaciclib 100 MG Oral Tablet [Verzenio]

abemaciclib 150 MG Oral Tablet

abemaciclib 150 MG Oral Tablet [Verzenio]

abemaciclib 200 MG Oral Tablet

abemaciclib 200 MG Oral Tablet [Verzenio]

abemaciclib 50 MG Oral Tablet

abemaciclib 50 MG Oral Tablet [Verzenio]

University of Iowa Hospitals Specialty Pharmacy

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