<section class="Section" data-sectioncode="34089-3"><a name="LINK_7ed0975d-d0c2-465e-aeef-d5e55e935595"></a><a name="section-8"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">Eptinezumab-jjmr is a humanized immunoglobulin G1 (IgG1) monoclonal antibody specific for calcitonin gene-related peptide (CGRP) ligand. Eptinezumab-jjmr has an approximate molecular weight of 143 kD. Eptinezumab-jjmr is produced in <span class="Italics">Pichia pastoris</span> yeast cells by recombinant DNA technology. </p><p>VYEPTI (eptinezumab-jjmr) injection is a sterile, preservative-free, clear to slightly opalescent, colorless to brownish-yellow solution, for intravenous infusion. VYEPTI is supplied as a 100 mg/mL single-dose vial. Each mL contains 100 mg eptinezumab-jjmr formulated in L-histidine (1 mg), L-histidine hydrochloride monohydrate (2.8 mg), polysorbate 80 (0.15 mg), sorbitol (40.5 mg), and Water for Injection, USP, at a pH of 5.8.</p></section>

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