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Alecensa® Alternatives

Alecensa®(Alectinib Hydrochloride)
®()
Prescription Only
Alecensa is a medication that belongs to the class of tyrosine kinase inhibitors and can be used to treat non-small cell lung cancer (NSCLC) caused by a mutation in the ALK gene....
Prescription Only
Dosage & AdministrationDosage & Administration comparison data
Administration
Dosing
Latin Shorthand
Financial AssistanceFinancial Assistance comparison data
Out-Of-Pocket Costs With Copay Card
Annual Cap
$25,000. Learn more.
Assistance Expiration
Generics
No lower-cost generic available
No lower-cost generic available
Physician AdvisoryPhysician Advisory comparison data
Adverse Reactions
The most common adverse reactions (incidence ≥20%) were fatigue, constipation, edema, myalgia, and anemia.. Learn more.
Mechanism of Actions (MoA)
Kinase inhibitors. Learn more.
Special Populations
Can ALECENSA be used during pregnancy?

No, ALECENSA can cause fetal harm when administered to a pregnant woman. It is advised to avoid using ALECENSA during pregnancy and advise pregnant women of the potential risk to a fetus.

Can ALECENSA be used during lactation?

No, there are no data on the presence of alectinib or its metabolites in human milk, the effects of alectinib on the breastfed infant, or its effects on milk production. It is advised to not breastfeed during treatment with ALECENSA and for 1 week after the final dose.

Should females and males of reproductive potential use contraception during treatment with ALECENSA?

Yes, females of reproductive potential should use effective contraception during treatment with ALECENSA and for 1 week after the final dose. Males with female partners of reproductive potential should also use effective contraception during treatment with ALECENSA and for 3 months following the final dose.

Is ALECENSA safe for pediatric use?

The safety and effectiveness of ALECENSA in pediatric patients have not been established.

Is ALECENSA safe for geriatric use?

Clinical studies of ALECENSA did not include a sufficient number of subjects aged 65 and older to determine whether they respond differently from younger subjects.

Is ALECENSA safe for use in patients with renal or hepatic impairment?

No dose adjustment is recommended for patients with mild or moderate renal impairment or mild (Child-Pugh A) or moderate (Child-Pugh B) hepatic impairment. However, the safety of ALECENSA in patients with severe renal impairment (creatinine clearance less than 30 mL/min) or end-stage renal disease and severe hepatic impairment (Child-Pugh C) is unknown.