Abraxane

(paclitaxel)

paclitaxel 100 MG Injection [Abraxane]

Dosage & administration

* Do not substitute ABRAXANE for other paclitaxel products. (2.1)
* Extravasation: Closely monitor the infusion site for extravasation and infiltration.
* Metastatic Breast Cancer (MBC): Recommended dosage of ABRAXANE is 260 mg/m2 intravenously over 30 minutes every 3 weeks.
* Non-Small Cell Lung Cancer (NSCLC): Recommended dosage of ABRAXANE is 100 mg/m2 intravenously over 30 minutes on Days 1, 8, and 15 of each 21-day cycle; administer carboplatin on Day 1 of each 21-day cycle immediately after ABRAXANE.
* Adenocarcinoma of the Pancreas: Recommended dosage of ABRAXANE is 125 mg/m2 intravenously over 30-40 minutes on Days 1, 8, and 15 of each 28-day cycle; administer gemcitabine on Days 1, 8, and 15 of each 28-day cycle immediately after ABRAXANE.
* Use in Patients with Hepatic Impairment: ABRAXANE is not recommended for use in patients with AST > 10 × ULN; or bilirubin > 5 × ULN or with metastatic adenocarcinoma of the pancreas who have moderate to severe hepatic impairment. For MBC or NSCLC, reduce starting dose in patients with moderate to severe hepatic impairment.
* Dose Reductions for Adverse Reactions: Dose reductions or discontinuation may be needed based on severe hematologic, neurologic, cutaneous, or gastrointestinal toxicities.

Most viewed Abraxane resources

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biomarker testing

Abraxane clinical details

Genetic testing requirements were obtained from the NCCN guidelines for each cancer type.

drug label

Abraxane prescribing information

Contact Medical Science Liaison Report Adverse Event

prior authorization

Abraxane prior authorization resources

Most recent Abraxane prior authorization forms

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Updated: May 30, 2023Cigna - Abraxane Prior Authorization Form

Updated: May 22, 2023Aetna - Medicare Part B Abraxane Prior Authorization Form

PDFComplete Letter of Medical Necessity

PDFCoverage Authorization Appeals

PDFCommercial Claim Denial Appeal/Redetermination Letter

PDFMedically Unlikely Edit (MUE) Letter

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Benefits investigation

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Reimbursement help (FRM)

OTHERReceive Assistance from an FRM Regarding Reimbursement Information

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financial assistance

Abraxane financial assistance options

Co-pay savings program

commercial only

PDFAbraxane Enrollment Form

PDFAbraxane Enrollment Form - Spanish

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Foundation programs

under insured

no insurance

goverment insurance

65+

PDFAbraxane Enrollment Form

PDFAbraxane Enrollment Form - Spanish

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.