What is the dosage of Abraxane?

Abraxane is available in 1 dosages, including 100 mg Injection

What does Abraxane treat?

Abraxane treats Breast Neoplasms, Non-Small-Cell Lung Carcinoma, Ovarian Neoplasms and Kaposi Sarcoma

What is Abraxane made of?

Abraxane contains paclitaxel which is a Microtubule Inhibitor

How is Abraxane administered?

Abraxane is administered as a Injectable

What is Abraxane mechanism of action?

Abraxane mechanism of action is

Dosage & Administration Drug label Prior authorization Financial assistance

Patient education

Abraxane

(paclitaxel)

paclitaxel 100 MG Injection [Abraxane]

BLACK BOX WARNING

Dosage & administration

* Do not substitute ABRAXANE for other paclitaxel products. (2.1)
* Extravasation: Closely monitor the infusion site for extravasation and infiltration.
* Metastatic Breast Cancer (MBC): Recommended dosage of ABRAXANE is 260 mg/m2 intravenously over 30 minutes every 3 weeks.
* Non-Small Cell Lung Cancer (NSCLC): Recommended dosage of ABRAXANE is 100 mg/m2 intravenously over 30 minutes on Days 1, 8, and 15 of each 21-day cycle; administer carboplatin on Day 1 of each 21-day cycle immediately after ABRAXANE.
* Adenocarcinoma of the Pancreas: Recommended dosage of ABRAXANE is 125 mg/m2 intravenously over 30-40 minutes on Days 1, 8, and 15 of each 28-day cycle; administer gemcitabine on Days 1, 8, and 15 of each 28-day cycle immediately after ABRAXANE.
* Use in Patients with Hepatic Impairment: ABRAXANE is not recommended for use in patients with AST > 10 × ULN; or bilirubin > 5 × ULN or with metastatic adenocarcinoma of the pancreas who have moderate to severe hepatic impairment. For MBC or NSCLC, reduce starting dose in patients with moderate to severe hepatic impairment.
* Dose Reductions for Adverse Reactions: Dose reductions or discontinuation may be needed based on severe hematologic, neurologic, cutaneous, or gastrointestinal toxicities.

Abraxane prescribing information

Have more Abraxane questions?

Submit MSL Request

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Need to report an Abraxane issue?

ONLINE FORMReport adverse event

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prior authorization

Abraxane Prior authorization resources

Complete Letter of Medical Necessity

NOT PROVIDED BY BRANDCoverage Authorization Request

Coverage Authorization Appeals

Commercial Claim Denial Appeal/Redetermination Letter

Medically Unlikely Edit (MUE) Letter

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Benefits investigation

Abraxane Enrollment Form

Abraxane Enrollment Form - Spanish

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Reimbursement help (FRM)

Receive Assistance from an FRM Regarding Reimbursement Information

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financial assistance

Abraxane Financial assistance options

Co-pay savings program

commercial only

Abraxane Enrollment Form

Abraxane Enrollment Form - Spanish

Enroll in Patient Savings Program

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

commercial only

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Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries

How to sign up

Typically HCP assisted enrollment (via form)

Foundation programs

under insured

no insurance

goverment insurance

65+

Abraxane Enrollment Form

Abraxane Enrollment Form - Spanish

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.

How to sign up

Patients submit proof of out-of-pocket drug costs to charities for reimbursement

patient education

Abraxane Patient education

Getting started on Abraxane

NOT PROVIDED BY BRANDInstructions For Use: Metastatic Pancreatic Cancer

NOT PROVIDED BY BRANDInstructions For Use: Metastatic Breast Cancer

NOT PROVIDED BY BRANDInstructions For Use: 1L Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)