<section class="Section" data-sectioncode="34089-3"><a name="LINK_2c8e4016-3376-4164-bb3b-b7547946b92d"></a><a name="section-8"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">Fremanezumab-vfrm is a fully humanized IgG2Δa/kappa monoclonal antibody specific for calcitonin gene-related peptide (CGRP) ligand. Fremanezumab-vfrm is produced by recombinant DNA technology in Chinese hamster ovary (CHO) cells. The antibody consists of 1324 amino acids and has a molecular weight of approximately 148 kDa.</p><p>AJOVY (fremanezumab-vfrm) injection is a sterile, preservative-free, clear to opalescent, colorless to slightly yellow solution for subcutaneous injection, supplied in a single-dose 225 mg/1.5 mL prefilled autoinjector and a single-dose 225 mg/1.5 mL prefilled syringe. </p><p>Each prefilled autoinjector or prefilled syringe delivers 1.5 mL of solution containing 225 mg fremanezumab-vfrm, disodium ethylenediaminetetraacetic acid dihydrate (EDTA) (0.204 mg), L-histidine (0.815 mg), L-histidine hydrochloride monohydrate (3.93 mg), polysorbate-80 (0.3 mg), sucrose (99 mg), and Water for Injection, and has a pH of 5.5.</p></section>

AJOVY

1.5 ML fremanezumab-vfrm 150 MG/ML Auto-Injector

1.5 ML fremanezumab-vfrm 150 MG/ML Auto-Injector [Ajovy]

1.5 ML fremanezumab-vfrm 150 MG/ML Prefilled Syringe

1.5 ML fremanezumab-vfrm 150 MG/ML Prefilled Syringe [Ajovy]

Ajovy

fremanezumab

Advance Medical Rx Inc.

Actemra

Benlysta

Enbrel

Stelara

Ajovy | Advance Medical Rx Inc.

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