<section class="Section" data-sectioncode="34089-3"><a name="LINK_2c8e4016-3376-4164-bb3b-b7547946b92d"></a><a name="section-8"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">Fremanezumab-vfrm is a fully humanized IgG2Δa/kappa monoclonal antibody specific for calcitonin gene-related peptide (CGRP) ligand. Fremanezumab-vfrm is produced by recombinant DNA technology in Chinese hamster ovary (CHO) cells. The antibody consists of 1324 amino acids and has a molecular weight of approximately 148 kDa.</p><p>AJOVY (fremanezumab-vfrm) injection is a sterile, preservative-free, clear to opalescent, colorless to slightly yellow solution for subcutaneous injection, supplied in a single-dose 225 mg/1.5 mL prefilled autoinjector and a single-dose 225 mg/1.5 mL prefilled syringe. </p><p>Each prefilled autoinjector or prefilled syringe delivers 1.5 mL of solution containing 225 mg fremanezumab-vfrm, disodium ethylenediaminetetraacetic acid dihydrate (EDTA) (0.204 mg), L-histidine (0.815 mg), L-histidine hydrochloride monohydrate (3.93 mg), polysorbate-80 (0.3 mg), sucrose (99 mg), and Water for Injection, and has a pH of 5.5.</p></section>

AJOVY

fremanezumab-vfrm

fremanezumab

1.5 ML fremanezumab-vfrm 150 MG/ML Prefilled Syringe

Ajovy

1.5 ML fremanezumab-vfrm 150 MG/ML Prefilled Syringe [Ajovy]

1.5 ML fremanezumab-vfrm 150 MG/ML Auto-Injector

1.5 ML fremanezumab-vfrm 150 MG/ML Auto-Injector [Ajovy]

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Ajovy is a prescription medication that can be self-injected once a month or once every three months under the skin to prevent migraine headaches. The most commonly reported side effect is injection site reactions. Ajovy does not seem to cause constipation. Additionally, there are no known drug interactions.

Ajovy is FDA approved for the following indications: Migraine prevention. 


Report Adverse Event 

Prescribing Information

Medication Guide 

Submit MSL Request 

Pharmacy List 

Formulary Information

Coverage Authorization Request 

Coverage Authorization Appeals

Letter of Medical Necessity 

Enroll in Patient Savings Program 

Teva Patient Assistance Program 

Other HCP Resources 

About Ajovy 

Side Effects 

Taking Ajovy 

Patient Stories 

Patient Resources: Patients Considering Ajovy 

Patient Resources: Patients On Ajovy 

Instructions For Use (Prefilled Syringe) : Migraine Prevention 

Instructions For Use (Prefilled Autoinjector): Migraine Prevention 

Sharps Container

Doctor Discussion Guide: Patients Considering Ajovy

Migraine Tracker 