Ayvakit

(avapritinib)

avapritinib 100 MG Oral Tablet [Ayvakit]avapritinib 200 MG Oral Tablet [Ayvakit]

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NO BLACK BOX WARNING

Dosage & administration

* GIST: Select patients for treatment with AYVAKIT based on the presence of a PDGFRA exon 18 mutation.
* GIST: The recommended dosage is 300 mg orally once daily.
* AdvSM: The recommended dosage is 200 mg orally once daily.

Most viewed Ayvakit resources

Enroll in Patient Savings Program

biomarker testing

Ayvakit clinical details

Genetic testing requirements were obtained from the NCCN guidelines for each cancer type.

drug label

Ayvakit prescribing information

Contact Medical Science Liaison Report Adverse Event

prior authorization

Ayvakit prior authorization resources

PDFComplete Letter of Medical Necessity

PDFCoverage Authorization Appeals

PDFAccess & Reimbursement Guide

PDFFormulary Exception Request

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Benefits investigation

PDFAyvakit Enrollment Form

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Reimbursement help (FRM)

OTHERReceive Assistance from an FRM Regarding Reimbursement Information

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pharmacy

Ayvakit preferred pharmacy

OTHERPharmacy List

financial assistance

Ayvakit financial assistance options

Co-pay savings program

commercial only

Enroll in Patient Savings Program

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

commercial only

PDFAyvakit Enrollment Form

OTHEREnroll in Bridge Program

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Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries

How to sign up

Typically HCP assisted enrollment (via form)

Foundation programs

under insured

no insurance

goverment insurance

65+

PDFAyvakit Enrollment Form

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.

How to sign up

Patients submit proof of out-of-pocket drug costs to charities for reimbursement

patient education

Ayvakit patient education

Getting started on Ayvakit

To share resource; ask patient to:

1.Pull out phone

2.Open camera

3.Scan QR code with camera

4.Tap link