What is the dosage of Bosulif?

Bosulif is available in 3 dosages, including 100 mg Tab, 400 mg Tab and 500 mg Tab

What does Bosulif treat?

Bosulif treats BCR-ABL Positive Chronic Myelogenous Leukemia

What is Bosulif made of?

Bosulif contains bosutinib which is a Kinase Inhibitor

How is Bosulif administered?

Bosulif is administered as a Oral Pill

What is Bosulif mechanism of action?

Bosulif mechanism of action is P-Glycoprotein Inhibitors or Protein Kinase Inhibitors

Dosage & Administration Drug label Samples Prior authorization Financial assistance

Patient education

Bosulif

(bosutinib)

bosutinib 100 MG Oral Tablet [Bosulif]bosutinib 400 MG Oral Tablet [Bosulif]

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NO BLACK BOX WARNING

Dosage & administration

* Newly-diagnosed chronic phase Ph+ CML: 400 mg orally once daily with food.
* Chronic, accelerated, or blast phase Ph+ CML with resistance or intolerance to prior therapy: 500 mg orally once daily with food.
* Consider dose escalation by increments of 100 mg once daily to a maximum of 600 mg daily in patients who do not reach complete hematologic, cytogenetic, or molecular response and do not have Grade 3 or greater adverse reactions.
* Adjust dosage for toxicity and organ impairment

Bosulif prescribing information

Have more Bosulif questions?

Submit MSL Request

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Need to report a Bosulif issue?

ONLINE FORMReport adverse event

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samples

Request Bosulif samples

Online Sample Form

Sample Request

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prior authorization

Bosulif Prior authorization resources

Complete Letter of Medical Necessity

NOT PROVIDED BY BRANDCoverage Authorization Request

NOT PROVIDED BY BRANDComplete Coverage Authorization appeals

Coverage Authorization Appeal

Formulary Exception Letter

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Benefits investigation

Pfizer Oncology Together Form

Pfizer Oncology Together Form - Spanish

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Reimbursement help (FRM)

Receive Assistance from an FRM Regarding Reimbursement Information

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financial assistance

Bosulif Financial assistance options

Co-pay savings program

commercial only

Enroll in Patient Savings Program

HCP Office : Attest & Print Co-Pay Card

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

commercial only

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Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries

How to sign up

Typically HCP assisted enrollment (via form)

Foundation programs

under insured

no insurance

goverment insurance

65+

Pfizer Oncology Together Form

Pfizer Oncology Together Form - Spanish

Pfizer Patient Assistance Program

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.

How to sign up

Patients submit proof of out-of-pocket drug costs to charities for reimbursement

patient education

Bosulif Patient education

Getting started on Bosulif

NOT PROVIDED BY BRANDInstructions For Use: Adults with CP Ph+ CML

NOT PROVIDED BY BRANDInstructions For Use: Ph+ CML in Adults With Resistance or Intolerance to Prior Therapy