What is the dosage of Briumvi?

Briumvi is available in 1 dosages, including 25 mg/ml Injection 6 ml

What is Briumvi mechanism of action?

Briumvi mechanism of action is CD20-directed Antibody Interactions

Briumvi Prescribing & Dosing Schedule

Q: What does Briumvi treat?

Briumvi treats Demyelinating Diseases, Multiple Sclerosis, Chronic Progressive and Multiple Sclerosis, Relapsing-Remitting

Q: What is Briumvi made of?

Briumvi contains ublituximab which is a CD20-directed Cytolytic Antibody

Q: How is Briumvi administered?

Briumvi is administered as a Injectable

Dosage & Administration

* Hepatitis B virus screening and quantitative serum immunoglobulin screening are required before first dose (2.1).
* Pre-medicate with methylprednisolone (or an equivalent corticosteroid) and an antihistamine (e.g., diphenhydramine) prior to each infusion (2.2).
* Administer BRIUMVI by intravenous infusion.
* First Infusion: 150 mg intravenous infusion ( 2.3)
* Second Infusion: 450 mg intravenous infusion two weeks after the first infusion ( 2.3)
* Subsequent Infusions: 450 mg intravenous infusion 24 weeks after the first infusion and every 24 weeks thereafter ( 2.3)

* Must be diluted in 0.9% Sodium Chloride Injection, USP prior to administration (2.3, 2.6).
* Monitor patients closely during and for at least one hour after the completion of the first two infusions. Post-infusion monitoring of subsequent infusions is at physician discretion unless infusion reaction and/or hypersensitivity has been observed (2.3, 5.1).

Get Your Patient on Briumvi

See your patient's specific prior authorization requirements including coverage restrictions and step therapies

Or select your Insurance from the list below:

Briumvi Prescribing Information

Contact Medical Science Liaison

Report Adverse Event

Briumvi Prior Authorization Resources

Most recent state uniform prior authorization forms

Verified: Sep 24, 2024Arizona - Uniform Prior Authorization Form

Verified: Sep 24, 2024Colorado - Uniform Prior Authorization Form

Verified: Sep 24, 2024Hawaii - Uniform Prior Authorization Form

Verified: Sep 24, 2024Illinois - Uniform Prior Authorization Form

Verified: Sep 24, 2024Indiana - Uniform Prior Authorization Form

Verified: Sep 24, 2024Louisiana - Uniform Prior Authorization Form

Verified: Sep 24, 2024Minnesota - Uniform Prior Authorization Form

Verified: Sep 24, 2024New Hampshire - Uniform Prior Authorization Form

Verified: Sep 24, 2024New Mexico - Uniform Prior Authorization Form

Verified: Sep 24, 2024Oregon - Uniform Prior Authorization Form

Verified: Sep 24, 2024Texas - Uniform Prior Authorization Form

Verified: Oct 05, 2024Washington - Uniform Prior Authorization Form

Verified: Oct 05, 2024Wisconsin - Uniform Prior Authorization Form

Coverage Authorization Appeals

Complete Letter of Medical Necessity

Benefits investigation

Briumvi Start Form

Briumvi Preferred Pharmacy

Pharmacy List

Briumvi Financial Assistance Options

Copay savings program

Briumvi Start Form

Enroll in Patient Savings Program - Only HCP can enroll patients

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

Briumvi Start Form

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Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries

How to sign up

Typically HCP assisted enrollment (via form)

Foundation programs

Briumvi Start Form

Patient Asssitance Program

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and copays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.