What is the dosage of Carbaglu?

Carbaglu is available in 1 dosages, including 200 mg Tab

What is Carbaglu made of?

Carbaglu contains carglumic acid which is a Carbamoyl Phosphate Synthetase 1 Activator

How is Carbaglu administered?

Carbaglu is administered as a Oral Suspension Tablet

What is Carbaglu mechanism of action?

Carbaglu mechanism of action is Carbamoyl Phosphate Synthetase 1 Activators

Dosage & Administration Drug label Samples Prior authorization Financial assistance

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Carbaglu

(carglumic acid)

carglumic acid 200 MG Tablet for Oral Suspension [Carbaglu]

NO BLACK BOX WARNING

Dosage & administration

Acute Hyperammonemia due to NAGS deficiency

* The recommended pediatric and adult dosage is 100 mg/kg/day to 250 mg/kg/day divided into 2 to 4 doses and rounded to the nearest 100 mg.

Chronic Hyperammonemia due to NAGS deficiency

* The recommended pediatric and adult dosage is 10 mg/kg/day to 100 mg/kg/day divided into 2 to 4 doses and rounded to the nearest 100 mg.

Therapeutic Monitoring for NAGS Deficiency

* Closely monitor plasma ammonia and titrate dosage to maintain the ammonia level within normal range for the patient's age, taking into consideration their clinical condition.

Acute Hyperammonemia due to PA or MMA

* The recommended pediatric and adult dosage is:
* 150 mg/kg/day for patients less than or equal to 15 kg
* 3.3 g/m2/day for patients greater than 15 kg

* Divide the daily dosage into two equal doses and round up to the nearest 50 mg; administer each dose 12 hours apart.
* Continue treatment until ammonia level is less than 50 micromol/L and for a maximum duration of 7 days.

See Full Prescribing Information for Instructions on Dosage Adjustment in Patients with Renal Impairment

Preparation and Administration

* Disperse CARBAGLU tablets in water. Do not swallow whole or crushed.
* Take immediately before meals or feedings.
* For additional instructions on preparation and administration orally or through a nasogastric tube or gastrostomy tube, see Full Prescribing Information.

Carbaglu prescribing information

Need to report a Carbaglu issue?

ONLINE FORMReport adverse event

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samples

Request Carbaglu samples

NOT PROVIDED BY BRANDView Online Sample Form

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prior authorization

Carbaglu Prior authorization resources

NOT PROVIDED BY BRANDComplete Letter of Medical Necessity

NOT PROVIDED BY BRANDCoverage Authorization Request

NOT PROVIDED BY BRANDCoverage Authorization Appeals

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Benefits investigation

Carbaglu Prescription & Enrollment Form

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Reimbursement help (FRM)

NOT PROVIDED BY BRANDReimbursement help (FRM) resources

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financial assistance

Carbaglu Financial assistance options

Co-pay savings program

commercial only

Enroll in Patient Savings Program

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

commercial only

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Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries

How to sign up

Typically HCP assisted enrollment (via form)

Foundation programs

under insured

no insurance

goverment insurance

65+

Carbaglu Patient Assistance Program

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.

How to sign up

Patients submit proof of out-of-pocket drug costs to charities for reimbursement

patient education

Carbaglu Patient education

Getting started on Carbaglu

Instructions For Use - NAGS Deficiency

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

Instructions For Use - Propionic Acidemia (PA) and Methylmalonic Acidemia (MMA)

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

Patient toolkit

About Carbaglu

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

Patient Resources

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

Learn More

Can't find what you're looking for?

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Please note:

Access to a Field Reimbursement Manager (FRM) or Medical Science Liaison (MSL) varies by brand and may require talking with your rep first.
Samples are provided at the discretion of the brand.
We are unable to collect Protected Health Information (PHI), fill out forms, or submit them on your behalf.

Carbaglu

Dosage & administration

Most viewed Carbaglu resources

drug label

Carbaglu prescribing information

Need to report a Carbaglu issue?

samples

Request Carbaglu samples

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How do I find out who my Carbaglu rep is?

prior authorization

Carbaglu Prior authorization resources

Benefits investigation

Reimbursement help (FRM)

financial assistance

Carbaglu Financial assistance options

Co-pay savings program

Overview

Patient benefit

Patient eligibility

How to sign up

Bridge program

Overview

Patient benefit

Patient eligibility

How to sign up

Foundation programs

Overview

Patient benefit

Patient eligibility

How to sign up

patient education

Carbaglu Patient education

Getting started on Carbaglu

Patient toolkit

Can't find what you're looking for?