Carbaglu Prescribing & Dosing Schedule

Dosage & Administration Drug label Prior authorization Pharmacy Financial assistance Patient education People also ask

Carbaglu (carglumic acid)

Carbaglu 200 MG Tablet for Oral Suspension

NO BOXED WARNING

Dosage & Administration

Acute Hyperammonemia due to NAGS deficiency

* The recommended dosage in adult and pediatric patients is 100 mg/kg to 250 mg/kg orally daily. Divide the daily dosage into 2 to 4 doses.

Chronic Hyperammonemia due to NAGS deficiency

* The recommended dosage in adult and pediatric patients is 10 mg/kg to 100 mg/kg orally daily. Divide the daily dosage into 2 to 4 doses.

Therapeutic Monitoring for NAGS Deficiency

* Closely monitor plasma ammonia and titrate dosage to maintain the ammonia level within normal range for the patient's age, taking into consideration their clinical condition.

Acute Hyperammonemia due to PA or MMA

* The recommended dosage in adult and pediatric patients is:
* 150 mg/kg orally daily for patients less than or equal to 15 kg
* 3.3 g/m2 orally daily for patients greater than 15 kg

* Divide the daily dosage into 2 doses.
* Continue treatment until ammonia level is less than 50 micromol/L and for a maximum duration of 7 days.

Patients with Renal Impairment

* See Full Prescribing Information for Instructions on Dosage Adjustment.

Preparation and Administration

* Disperse CARBAGLU tablets in water. Do not swallow whole or crushed.
* Take immediately before meals or feedings.
* For additional instructions on preparation and administration orally or through a nasogastric tube or gastrostomy tube, see Full Prescribing Information.

drug label

Carbaglu Prescribing Information

Contact Medical Science Liaison

Report Adverse Event

prior authorization

Carbaglu Prior Authorization Resources

Most recent state uniform prior authorization forms

Verified: Jun 26, 2024Arizona - Uniform Prior Authorization Form

Verified: Jun 26, 2024Colorado - Uniform Prior Authorization Form

Verified: Jun 26, 2024Hawaii - Uniform Prior Authorization Form

Verified: Jul 26, 2024Illinois - Uniform Prior Authorization Form

Verified: Jun 26, 2024Indiana - Uniform Prior Authorization Form

Verified: Jun 26, 2024Louisiana - Uniform Prior Authorization Form

Verified: Jun 26, 2024Minnesota - Uniform Prior Authorization Form

Verified: Jun 26, 2024New Hampshire - Uniform Prior Authorization Form

Verified: Jun 26, 2024New Mexico - Uniform Prior Authorization Form

Verified: Jun 26, 2024Oregon - Uniform Prior Authorization Form

Verified: Jun 26, 2024Texas - Uniform Prior Authorization Form

Verified: Jul 07, 2024Washington - Uniform Prior Authorization Form

Verified: Jul 07, 2024Wisconsin - Uniform Prior Authorization Form

Complete Letter of Medical Necessity

Appeals Tips & Checklist

Letter of Medical Necessity: NAGS

Benefits investigation

Carbaglu Prescription & Enrollment Form

pharmacy

Carbaglu Preferred Pharmacy

Pharmacy List

financial assistance

Carbaglu Financial Assistance Options

Copay savings program

Carbaglu Prescription & Enrollment Form

Enroll in Patient Savings Program

Learn More

Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Foundation programs

Carbaglu Prescription & Enrollment Form

Carbaglu Patient Assistance Program

Learn More

Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and copays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.

How to sign up

Patients submit proof of out-of-pocket drug costs to charities for reimbursement

patient education

Carbaglu Patient Education

Getting started on Carbaglu

Instructions For Use: NAGS Deficiency

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

Instructions For Use: Propionic Acidemia (PA) and Methylmalonic Acidemia (MMA)

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

To share resource; ask patient to:

1.Pull out phone

2.Open camera

3.Scan QR code with camera

4.Tap link

Patient toolkit

About Carbaglu

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

View How to Take Carbaglu

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

Patient Stories: NAGS

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

Patient Resources

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

Carbaglu FAQs

How is the dosage of Carbaglu ?Carbaglu is available in 1 dosages, including 200 mg Tab

What does Carbaglu treat?Carbaglu treats Hyperammonemia

What is Carbaglu made of?Carbaglu contains carglumic acid which is a Carbamoyl Phosphate Synthetase 1 Activator

How Is Carbaglu Administered?Carbaglu is administered as a Oral Suspension Tablet

What Are The Carbaglu Mechanism Of Action?Carbaglu mechanism of action is Carbamoyl Phosphate Synthetase 1 Activators

FAQ Data Source

Dosage & Administration

Dosage & Administration

drug label

Carbaglu Prescribing Information

prior authorization

Carbaglu Prior Authorization Resources

Most recent state uniform prior authorization forms

Benefits investigation

pharmacy

Carbaglu Preferred Pharmacy

financial assistance

Carbaglu Financial Assistance Options

Copay savings program

Foundation programs

patient education

Carbaglu Patient Education

Getting started on Carbaglu

Patient toolkit

people also ask

Carbaglu FAQs