What is the dosage of Cholbam?

Cholbam is available in 2 dosages, including 250 mg Cap and 50 mg Cap

What does Cholbam treat?

Cholbam treats Zellweger Syndrome

What is Cholbam made of?

Cholbam contains cholic acid which is a Bile Acid

How is Cholbam administered?

Cholbam is administered as a Oral Pill

Dosage & Administration Drug label Prior authorization Financial assistance

Patient education

Cholbam

(cholic acid)

cholic acid 250 MG Oral Capsule [Cholbam]cholic acid 50 MG Oral Capsule [Cholbam]

NO BLACK BOX WARNING

Dosage & administration

* The recommended dosage is 10 to 15 mg/kg once daily or intwo divided doses, in pediatric patients and adults. See prescribinginformation for weight-based dosing tables.
* The recommended dosage in patients with concomitant familialhypertriglyceridemia is 11 to 17 mg/kg once daily or in two divideddoses and is adjusted based on clinical response
* Monitor AST, ALT, GGT, alkaline phosphatase, bilirubin andINR every month for the first 3 months, every 3 months for the next9 months, every 6 months during the next three years and annuallythereafter. Administer the lowest dose that effectively maintainsliver function.
* Discontinue CHOLBAM if liver function does not improve within3 months of starting treatment, if complete biliary obstruction develops,or if there are persistent clinical or laboratory indicators of worseningliver function or cholestasis; continue to monitor liver functionand consider restarting at a lower dose when parameters return tobaseline.

Administration Instructions:

* Take with food.
* Do not crush or chew the capsules. For patients unable toswallow the capsules, the capsules can be opened and the contentsmixed with drink/food

Cholbam prescribing information

Need to report a Cholbam issue?

ONLINE FORMReport adverse event

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prior authorization

Cholbam Prior authorization resources

NOT PROVIDED BY BRANDComplete Letter of Medical Necessity

NOT PROVIDED BY BRANDCoverage Authorization Request

NOT PROVIDED BY BRANDCoverage Authorization Appeals

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Benefits investigation

Cholbam Enrollment Form

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Reimbursement help (FRM)

NOT PROVIDED BY BRANDReimbursement help (FRM) resources

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financial assistance

Cholbam Financial assistance options

Co-pay savings program

commercial only

Enroll in Patient Savings Program

Cholbam Enrollment Form

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

commercial only

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Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries

How to sign up

Typically HCP assisted enrollment (via form)

Foundation programs

under insured

no insurance

goverment insurance

65+

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.

How to sign up

Patients submit proof of out-of-pocket drug costs to charities for reimbursement

patient education

Cholbam Patient education

Getting started on Cholbam

NOT PROVIDED BY BRANDInstructions For Use - Peroxisomal Biogenesis Disorder-Zellweger Spectrum Disorder (PBD-ZSD)

NOT PROVIDED BY BRANDInstructions For Use - Bile Acid Synthesis Disorders (BASD)

Patient toolkit

No-Cost Genetic Testing - Peroxisomal Biogenesis Disorder-Zellweger Spectrum Disorder (PBD-ZSD)

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

Patient Resources - Peroxisomal Biogenesis Disorder-Zellweger Spectrum Disorder (PBD-ZSD)

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

No-Cost Genetic Testing - Bile Acid Synthesis Disorders (BASD)

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

Patient Resources - Bile Acid Synthesis Disorders (BASD)

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

Learn More

Can't find what you're looking for?

Our trained staff can help you:

Please note:

Access to a Field Reimbursement Manager (FRM) or Medical Science Liaison (MSL) varies by brand and may require talking with your rep first.
Samples are provided at the discretion of the brand.
We are unable to collect Protected Health Information (PHI), fill out forms, or submit them on your behalf.

Cholbam

Dosage & administration

Most viewed Cholbam resources

drug label

Cholbam prescribing information

Need to report a Cholbam issue?

prior authorization

Cholbam Prior authorization resources

Benefits investigation

Reimbursement help (FRM)

financial assistance

Cholbam Financial assistance options

Co-pay savings program

Overview

Patient benefit

Patient eligibility

How to sign up

Bridge program

Overview

Patient benefit

Patient eligibility

How to sign up

Foundation programs

Overview

Patient benefit

Patient eligibility

How to sign up

patient education

Cholbam Patient education

Getting started on Cholbam

Patient toolkit

Can't find what you're looking for?