Bile Acid

Zellweger Syndrome

<section class="Section" data-sectioncode="34089-3"><a name="S11"></a><a name="section-11"></a><p></p><h1>11 DESCRIPTION</h1><p class="First"><a name="p6667111701586902316"></a>Cholic acid is a bile acid. The chemical formula is C<span class="Sub">24</span>H<span class="Sub">40</span>O<span class="Sub">5</span>, the molecular weight is 408.57 and the chemical structure is:</p><p></p><div class="Figure"><img alt="Chemical Structure" src="cholbam-01.jpg"/></div><p><a name="p6684111701586902316"></a>Cholic acid is a white to off-white powder. It is practically insoluble in water and in 0.1 M HCl at 20°C and is sparingly soluble in 0.1 M NaOH at 20°C. It is soluble in glacial acetic acid, alcohols, and acetone. A saturated solution in water at 20°C has a pH of 4.4.</p><p><a name="p6687111701586902316"></a>CHOLBAM capsules contain 50 mg or 250 mg of cholic acid as the active ingredient in size 2 Swedish orange or size 0 white opaque gelatin capsules, respectively. Inactive ingredients in CHOLBAM include crospovidone, magnesium stearate, and silicified microcrystalline cellulose.</p><p>The size 2 capsule shells contain gelatin, red iron oxide and titanium dioxide, and the size 0 capsule shells contain gelatin and titanium dioxide. CHOLBAM is administered orally.</p></section>

Cholbam

cholic acid

cholic acid 250 MG Oral Capsule

cholic acid 50 MG Oral Capsule

cholic acid 250 MG Oral Capsule [Cholbam]

cholic acid 50 MG Oral Capsule [Cholbam]

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event 

Prescribing Information 

Pharmacy List 

Coverage Authorization Request 

Coverage Authorization Appeals 

Cholbam Enrollment Form

Enroll in Patient Savings Program 

Other HCP Resources: Peroxisomal Biogenesis Disorder-Zellweger Spectrum Disorder (PBD-ZSD)

Other HCP Resources: Bile Acid Synthesis Disorders (BASD)

About Cholbam: Peroxisomal Biogenesis Disorder-Zellweger Spectrum Disorder (PBD-ZSD)

Genetic Testing: Peroxisomal Biogenesis Disorder-Zellweger Spectrum Disorder (PBD-ZSD)

FAQs: Peroxisomal Biogenesis Disorder-Zellweger Spectrum Disorder (PBD-ZSD)

Patient Resources: Peroxisomal Biogenesis Disorder-Zellweger Spectrum Disorder (PBD-ZSD)

About Cholbam: Bile Acid Synthesis Disorders (BASD)

FAQs: Bile Acid Synthesis Disorders (BASD)

Genetic Testing: Bile Acid Synthesis Disorders (BASD)

Patient Resources: Bile Acid Synthesis Disorders (BASD)

Total Care Hub Support Program

Instructions For Use: Peroxisomal Biogenesis Disorder-Zellweger Spectrum Disorder (PBD-ZSD)

Instructions For Use: Bile Acid Synthesis Disorders (BASD)

Instructions For Use: Smith-Lemli-Opitz Syndrome (SLOS)