Clarithromycin
Clarithromycin Prescribing Information
Contraindications, Lomitapide, Lovastatin, and Simvastatin (4.5) 9/2019
Warnings and Precautions, QT Prolongation (5.2) 11/2018
Warnings and Precautions, Serious Adverse Reactions Due to Concomitant Use with Other Drugs (5.4) 9/2019
Warnings and Precautions, Embryo-fetal Toxicity (5.7) 12/2018
Clarithromycin tablets are a macrolide antimicrobial indicated for mild to moderate infections caused by designated, susceptible bacteria in the following:
• Acute Bacterial Exacerbation of Chronic Bronchitis in Adults (1.1)
• Acute Maxillary Sinusitis (1.2)
• Community-Acquired Pneumonia (1.3)
• Pharyngitis/Tonsillitis (1.4)
• Uncomplicated Skin and Skin Structure Infections (1.5)
• Acute Otitis Media in Pediatric Patients (1.6)
• Treatment and Prophylaxis of Disseminated Mycobacterial Infections (1.7)
•
•
•
•
•
• Reduce dose in moderate renal impairment with concomitant atazanavir or ritonavir-containing regimens and in severe renal impairment (2.6)
Clarithromycin tablets are available as:
·
·
- Hypersensitivity to clarithromycin or any macrolide drug (4.1)
- Cisapride, pimozide (4.2)
- History of cholestatic jaundice/hepatic dysfunction with use of clarithromycin (4.3)
- Colchicine in renal or hepatic impairment (4.4)
- Lomitapide, lovastatin, and simvastatin (4.5)
- Ergot alkaloids (ergotamine or dihydroergotamine) (4.6)