Seizures

<section class="Section" data-sectioncode="34089-3"><a name="ID_0a6dcba8-7a99-4698-868b-d1b1c24387cd"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION </h1><table border="1" cellpadding="4" cellspacing="0" class="Botrule" width="50%"><caption><span>Table 4. Description</span></caption><tbody class="Headless"><tr class="First"><td class="Botrule Lrule Rrule Toprule" valign="top">Proprietary Name</td><td class="Botrule Lrule Rrule Toprule" valign="top">DIACOMIT</td></tr><tr><td class="Botrule Lrule Rrule Toprule" valign="top">Established Name</td><td class="Botrule Lrule Rrule Toprule" valign="top">Stiripentol</td></tr><tr><td class="Botrule Lrule Rrule Toprule" valign="top">Route of Administration</td><td class="Botrule Lrule Rrule Toprule" valign="top">Oral</td></tr><tr><td class="Botrule Lrule Rrule Toprule" valign="top">Chemical Name</td><td class="Botrule Lrule Rrule Toprule" valign="top">4,4-dimethyl-1-[3,4-(methylendioxyphenyl)-1-pentene-3-ol</td></tr><tr class="Last"><td class="Botrule Lrule Rrule Toprule" valign="top">Structural Formula</td><td class="Botrule Lrule Rrule Toprule" valign="top"><img alt="formula" src="formula.jpg"/></td></tr></tbody></table><p class="First">Stiripentol is a white to pale yellow crystalline powder with a bitter taste; it is practically insoluble in water (at 25°C), sparingly soluble in chloroform, and soluble in acetone, ethanol, ether, acetonitrile, and dichloromethane. The melting point is approximately 75°C. The pKa is 14.2, and measurement of the partition coefficient (water-octanol) provides a Log P value of 2.94. The molecular formula is C<span class="Sub">14</span>H<span class="Sub">18</span>O<span class="Sub">3</span> and the molecular weight is 234.3.</p><p><span class="Underline">Capsules</span><br/>DIACOMIT capsules contain 250 mg (size 2: pink) or 500 mg (size 0: white) of stiripentol. Capsules also contain the following inactive ingredients: erythrosine (250 mg capsule only), gelatin, indigotine (250 mg capsule only), magnesium stearate, povidone, sodium starch glycolate, titanium dioxide.</p><p><span class="Underline">For Oral Suspension </span></p><p>DIACOMIT for oral suspension packets contain 250 mg or 500 mg of stiripentol. DIACOMIT packets also contain the following inactive ingredients: aspartame, carmellose sodium, erythrosine, glucose, hydroxyethylcellulose, povidone, sodium starch glycolate, sorbitol, titanium dioxide, fruit flavor (acacia, Bergamot oil, hypromellose, maltodextrin, sorbitol, and vanillin).</p></section>

Diacomit

stiripentol

stiripentol 250 MG Oral Capsule

stiripentol 250 MG Oral Capsule [Diacomit]

stiripentol 500 MG Oral Capsule

stiripentol 500 MG Oral Capsule [Diacomit]

stiripentol 500 MG Powder for Oral Suspension

stiripentol 500 MG Powder for Oral Suspension [Diacomit]

stiripentol 250 MG Powder for Oral Suspension

stiripentol 250 MG Powder for Oral Suspension [Diacomit]

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event 

Prescribing Information 

Medication Guide 

Pharmacy List

Coverage Authorization Request 

Coverage Authorization Appeals 

Letter of Medical Necessity 

Diacomit Patient Enrollment Form 

VA Enrollment Form 

Enroll in Patient Savings Program 

Enroll in Bridge Program 

Quick Start Program 

Diacomit Patient Assistance Program Application 

Other HCP Resources

About Diacomit 

Caregiver Resources 

Accessing Diacomit

Diacomit Discussion Guide

Diacomit Caregiver's Guide

Instructions For Use: Seizures due to Dravet's Syndrome 