What is the dosage of Enhertu?

Enhertu is available in 1 dosages, including 100 mg Injection

What does Enhertu treat?

Enhertu treats Breast Neoplasms and Gastrointestinal Neoplasms

What is Enhertu made of?

Enhertu contains trastuzumab which is a HER2/neu Receptor Antagonist

How is Enhertu administered?

Enhertu is administered as a Injectable

What is Enhertu mechanism of action?

Enhertu mechanism of action is HER2/Neu/cerbB2 Antagonists

Enhertu Prescribing & Dosing Schedule

Last Update: Oct, 21 2024

Enhertu(fam-trastuzumab deruxtecan-nxki)

ENHERTU 100 MG Injection

BOXED WARNING

Dosage & Administration

* Do not substitute ENHERTU for or with trastuzumab or ado-trastuzumab emtansine.
* For intravenous infusion only. Do not administer as an intravenous push or bolus. DO NOT use Sodium Chloride Injection, USP.
* Premedicate for prevention of chemotherapy-induced nausea and vomiting.
* The recommended dosage of ENHERTU for HER2-positive or HER2-low breast cancer, HER2-mutant NSCLC, and HER2-positive (IHC 3+) solid tumors is 5.4 mg/kg given as an intravenous infusion once every 3 weeks (21-day cycle) until disease progression or unacceptable toxicity.
* The recommended dosage of ENHERTU for HER2-positive gastric cancer is 6.4 mg/kg given as an intravenous infusion once every 3 weeks (21-day cycle) until disease progression or unacceptable toxicity.
* Management of adverse reactions (ILD, neutropenia, thrombocytopenia, or left ventricular dysfunction) may require temporary interruption, dose reduction, or discontinuation of ENHERTU.

Get Your Patient on Enhertu

See your patient's specific prior authorization requirements including coverage restrictions and step therapies

Or select your Insurance from the list below:

Enhertu Prescribing Information

Contact Medical Science Liaison

Report Adverse Event

Enhertu Prior Authorization Resources

Most recent state uniform prior authorization forms

Verified: Sep 24, 2024Arizona - Uniform Prior Authorization Form

Verified: Sep 24, 2024Colorado - Uniform Prior Authorization Form

Verified: Sep 24, 2024Hawaii - Uniform Prior Authorization Form

Verified: Sep 24, 2024Illinois - Uniform Prior Authorization Form

Verified: Sep 24, 2024Indiana - Uniform Prior Authorization Form

Verified: Sep 24, 2024Louisiana - Uniform Prior Authorization Form

Verified: Sep 24, 2024Minnesota - Uniform Prior Authorization Form

Verified: Sep 24, 2024New Hampshire - Uniform Prior Authorization Form

Verified: Sep 24, 2024New Mexico - Uniform Prior Authorization Form

Verified: Sep 24, 2024Oregon - Uniform Prior Authorization Form

Verified: Sep 24, 2024Texas - Uniform Prior Authorization Form

Verified: Oct 05, 2024Washington - Uniform Prior Authorization Form

Verified: Oct 05, 2024Wisconsin - Uniform Prior Authorization Form

Coverage Authorization Appeals

Enhertu PA Checklist

Complete Letter of Medical Necessity

Benefits investigation

Enhertu4u Enrollment Form

Enhertu4u Enrollment Form - Spanish

Enhertu Preferred Pharmacy

Pharmacy List

Enhertu Financial Assistance Options

Copay savings program

Enhertu4u Enrollment Form

Enhertu4u Enrollment Form - Spanish

Enroll in Patient Savings Program

Enroll in Patient Savings Program - HCP Office Online Portal

Learn More

Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Foundation programs

Patient Assistance Program Enrollment Form - English

Patient Assistance Program Enrollment Form - Spanish

Independent Financial Support Programs

Learn More

Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and copays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.