Epidiolex

(cannabidiol)

Epidiolex 100 MG/mL Oral Solution

NO BLACK BOX WARNING

Dosage & administration

* Obtain serum transaminases (ALT and AST) and total bilirubin levels in all patients prior to starting treatment.
* See Full Prescribing Information for titration.

Seizures Associated with Lennox-Gastaut Syndrome or Dravet Syndrome

* The recommended starting dosage is 2.5 mg/kg by mouth twice daily (5 mg/kg/day). After one week, the dosage can be increased to a maintenance dosage of 5 mg/kg twice daily (10 mg/kg/day).
* Based on individual clinical response and tolerability, EPIDIOLEX can be increased up to a maximum recommended maintenance dosage of 10 mg/kg twice daily (20 mg/kg/day).

Seizures Associated with Tuberous Sclerosis Complex

* The recommended starting dosage is 2.5 mg/kg by mouth twice daily (5 mg/kg/day). Increase the dose weekly by 2.5 mg/kg twice daily (5 mg/kg/day), as tolerated, to a recommended maintenance dosage of 12.5 mg/kg twice daily (25 mg/kg/day).

drug label

Epidiolex prescribing information

Contact Medical Science Liaison Report Adverse Event

prior authorization

Epidiolex prior authorization resources

Most recent Epidiolex prior authorization forms

View By Payer

Verified: Sep 27, 2023Cigna - Epidiolex Prior Authorization Form

OTHERComplete Letter of Medical Necessity

PDFCoverage Authorization Request - Through CoverMyMeds

OTHERLetter of Medical Exception

PDFEpidiolex Start Form

PDFEpidiolex Start Form - Spanish

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Benefits investigation

PDFEpidiolex Start Form

PDFEpidiolex Start Form - Spanish

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Reimbursement help (FRM)

OTHERReceive Assistance from an FRM Regarding Reimbursement Information

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pharmacy

Epidiolex preferred pharmacy

OTHERPharmacy List

financial assistance

Epidiolex financial assistance options

Co-pay savings program

commercial only

OTHEREnroll in Patient Savings Program

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

commercial only

PDFEpidiolex Start Form

PDFEpidiolex Start Form - Spanish

OTHERBridge (QuickStart) Program

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Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries