Dosage & Administration Biomarker testing Drug label Prior authorization Pharmacy Financial assistance

Gavreto

(pralsetinib)

GAVRETO 100 MG Oral Capsule

NO BLACK BOX WARNING

Dosage & administration

Select patients for treatment with GAVRETO based on the presence of a RET gene fusion or gene mutation.

The recommended dosage in adults and pediatric patients 12 years and older is 400 mg orally once daily on an empty stomach (no food intake for at least 2 hours before and at least 1 hour after taking GAVRETO).

biomarker testing

Gavreto clinical details

Genetic testing requirements were obtained from the NCCN guidelines for each cancer type.

drug label

Gavreto prescribing information

Contact Medical Science Liaison Report Adverse Event

prior authorization

Gavreto prior authorization resources

OTHERComplete Letter of Medical Necessity

OTHERCoverage Authorization Appeals

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Benefits investigation

PDFPrescriber Service & Patient Consent Form

Prescriber Service Form - Online Portal

PDFPatient Consent Form - English

PDFPatient Consent Form - Spanish

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pharmacy

Gavreto preferred pharmacy

OTHERPharmacy List

financial assistance

Gavreto financial assistance options

Co-pay savings program

commercial only

PDFPrescriber Service & Patient Consent Form

Prescriber Service Form - Online Portal

PDFPatient Consent Form - English

PDFPatient Consent Form - Spanish

Enroll in Patient Savings Program

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

commercial only

PDFPrescriber Service & Patient Consent Form

Prescriber Service Form - Online Portal

PDFPatient Consent Form - English

PDFPatient Consent Form - Spanish

OTHERGavreto Sure Start Program

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Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries

How to sign up

Typically HCP assisted enrollment (via form)

Foundation programs

under insured

no insurance

goverment insurance

65+

PDFPrescriber Service & Patient Consent Form

Prescriber Service Form - Online Portal

PDFPatient Consent Form - English

PDFPatient Consent Form - Spanish

PDFGenentech Patient Foundation Application Form - Prescriber Form

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.