Dosage & Administration Drug label Financial assistance

Hysingla

(hydrocodone)

Hysingla ER 20 MG 24HR Extended Release Oral TabletHysingla ER 30 MG 24HR Extended Release Oral Tablet

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Dosage & administration

* To be prescribed only by healthcare providers knowledgeablein use of potent opioids for management of chronic pain.
* Daily doses of HYSINGLA ER greater than or equal to 80 mgare only for use in patients in whom tolerance to an opioid of comparablepotency has been established.
* Patients considered opioid-tolerant are those taking, forone week or longer, at least 60 mg oral morphine per day, 25 mcg transdermalfentanyl per hour, 30 mg oral oxycodone per day, 8 mg oral hydromorphoneper day, 25 mg oral oxymorphone per day, 60 mg oral hydrocodone perday, or an equianalgesic dose of another opioid.
* Use the lowest effective dosage for the shortest durationconsistent with individual patient treatment goals .
* Individualize dosing based on the severity of pain, patientresponse, prior analgesic experience, and risk factors for addiction,abuse, and misuse.
* Instruct patients to swallow HYSINGLA ER intact, and notto crush, chew, or dissolve the tablets (risk of potentially fataloverdose).
* Instruct patients to take tablets one at a time, with enoughwater to ensure complete swallowing immediately after placing in themouth
* Discuss availability of naloxone with the patient and caregiverand assess each patient’s need for access to naloxone, both when initiatingand renewing treatment with HYSINGLA ER. Consider prescribing naloxonebased on the patient’s risk factors for overdose (2.2, 5.1, 5.3, 5.6).
* For opioid-naïve patients, initiate with 20 mg tablets orallyevery 24 hours.
* To convert to HYSINGLA ER from another opioid, follow theconversion instructions to obtain an estimated dose.
* Dose titration of HYSINGLA ER may occur every 3 to 5 days
* Patients with Severe Hepatic Impairment: Initiate dosing with one half of the recommended starting dosageand titrate carefully. Monitor for respiratory depression, sedation,and hypotension.
* Patients with Moderate to Severe Renal Impairmentand End-Stage Renal Disease: Initiate dosing at one halfthe recommended starting dosage and titrate carefully. Monitor forsigns of respiratory depression, sedation, and hypotension.
* Do not abruptly discontinue HYSINGLA ER in a physicallydependent patient because rapid discontinuation of opioid analgesicshas resulted in serious withdrawal symptoms, uncontrolled pain, andsuicide.

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Hysingla prescribing information

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Hysingla financial assistance options

Co-pay savings program

commercial only

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

patient education

Hysingla patient education

Getting started on Hysingla

To share resource; ask patient to:

1.Pull out phone

2.Open camera

3.Scan QR code with camera

4.Tap link

Patient toolkit

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Other resources

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Hysingla FAQs

How is the dosage of Hysingla?Hysingla is available in 7 dosages, including 100 mg Abuse-Deterrent 24 HR XR Tab, 120 mg Abuse-Deterrent 24 HR XR Tab, 20 mg Abuse-Deterrent 24 HR XR Tab, 30 mg Abuse-Deterrent 24 HR XR Tab, 40 mg Abuse-Deterrent 24 HR XR Tab, 60 mg Abuse-Deterrent 24 HR XR Tab and 80 mg Abuse-Deterrent 24 HR XR Tab

What does Hysingla treat?Hysingla treats Cough, Obstructive Lung Diseases and Postoperative Pain

What is Hysingla made of?Hysingla contains hydrocodone which is a Opioid Agonist

How Is Hysingla Administered?Hysingla is administered as a Oral Pill

What Are The Hysingla Mechanism Of Action?Hysingla mechanism of action is Opioid Agonists

FAQ Data Source

Hysingla

Dosage & administration

drug label

Hysingla prescribing information

financial assistance

Hysingla financial assistance options

Co-pay savings program

patient education

Hysingla patient education

Getting started on Hysingla

Patient toolkit

Other resources

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Hysingla FAQs