What is the dosage of Imbruvica?

Imbruvica is available in 7 dosages, including 140 mg Cap, 140 mg Tab, 280 mg Tab, 420 mg Tab, 560 mg Tab, 70 mg Cap and 70 mg/ml Susp

What does Imbruvica treat?

Imbruvica treats Waldenstrom Macroglobulinemia, B-Cell Chronic Lymphocytic Leukemia, B-Cell Lymphoma and Mantle-Cell Lymphoma

What is Imbruvica made of?

Imbruvica contains ibrutinib which is a Kinase Inhibitor

How is Imbruvica administered?

Imbruvica is administered as a Oral Pill or Oral Liquid

What is Imbruvica mechanism of action?

Imbruvica mechanism of action is Protein Kinase Inhibitors

Dosage & Administration Drug label Samples Prior authorization Financial assistance

Patient education

Imbruvica

(ibrutinib)

ibrutinib 140 MG Oral Capsule [Imbruvica]ibrutinib 140 MG Oral Tablet [Imbruvica]

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NO BLACK BOX WARNING

Dosage & administration

* MCL and MZL: 560 mg taken orally once daily .

* CLL/SLL and WM: 420 mg taken orally once daily .

* cGVHD:
◦ Patients 12 years and older: 420 mg taken orally once daily .
◦ Patients 1 to less than 12 years of age: 240 mg/m2 taken orally once daily (up to a dose of 420 mg) .

Tablets or capsules should be taken orally with a glass of water. Do not open, break, or chew the capsules. Do not cut, crush, or chew the tablets. See full prescribing information for oral suspension administration instructions .

drug label

Imbruvica prescribing information

Have more Imbruvica questions?

Submit MSL Request

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Need to report an Imbruvica issue?

ONLINE FORMReport adverse event

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samples

Request Imbruvica samples

NOT PROVIDED BY BRANDView Online Sample Form

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prior authorization

Imbruvica Prior authorization resources

NOT PROVIDED BY BRANDComplete Letter of Medical Necessity

NOT PROVIDED BY BRANDCoverage Authorization Request

NOT PROVIDED BY BRANDCoverage Authorization Appeals

Letter of Medical Necessity: MCL

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Benefits investigation

Imbruvica By Your Side Enrollment Form - HCP

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Reimbursement help (FRM)

NOT PROVIDED BY BRANDReimbursement help (FRM) resources

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financial assistance

Imbruvica Financial assistance options

Co-pay savings program

commercial only

Imbruvica By Your Side Enrollment Form - HCP

Enroll in Patient Savings Program

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

commercial only

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Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries

How to sign up

Typically HCP assisted enrollment (via form)

Foundation programs

under insured

no insurance

goverment insurance

65+

J&J Patient Assistance Program - Eligibility Check

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.

How to sign up

Patients submit proof of out-of-pocket drug costs to charities for reimbursement